


Vol 24, No 1 (2025)
Original studies
Photochromotherapy in comprehensive treatment of children with chronic gastroduodenitis
Abstract
BACKGROUND: Photochromotherapy methods that restore impaired body functions provide a basis for their inclusion in the comprehensive treatment of children with chronic gastroduodenitis.
AIM: To develop and justify the use of narrow-band optical radiation at 650 nm and 540 nm as part of comprehensive treatment of chronic gastroduodenitis in children.
MATERIALS AND METHODS: An open, randomized, controlled prospective study was conducted, including 80 children with chronic gastroduodenitis. Using simple randomization, the children were divided into three groups. The first group (n=30) received narrow-band optical radiation at 650 nm from the Spectr device in combination with pharmacotherapy. The second group (n=30) underwent treatment with pharmacological agents combined with narrow-band optical radiation at 540 nm from the Spectr device. The control group consisted of 20 children who only received pharmacotherapy.
RESULTS: Statistical analysis demonstrated that incorporating photochromotherapy methods into the comprehensive treatment of children with chronic gastroduodenitis significantly reduced the frequency of pain syndrome (p <0.01), dyspeptic syndrome (p <0.01), and asthenovegetative syndrome (p <0.01). Additionally, it improved the propulsion function of the intestines (p <0.01).
CONCLUSION: The inclusion of photochromotherapy in the comprehensive treatment of children with chronic gastroduodenitis significantly contributes to the restoration of the mucous membrane in the upper gastrointestinal tract and has a positive effect on the motor function of the gallbladder.



Instrumental gait analysis in children with psoriatic arthritis using inertial sensors
Abstract
BACKGROUND: Instrumental gait analysis (IGA) provides an objective and quantitative assessment of characteristic human movement patterns.
AIM: To analyze quantitative IGA parameters using inertial sensors in children with psoriatic arthritis (PsA) to identify early diagnostic markers and assess their potential application in evaluating the effectiveness of medical rehabilitation methods.
MATERIALS AND METHODS: The study included 34 children aged 11 to 17 years. The study group consisted of 17 children diagnosed with psoriasis and PsA (n=17). The control group included 17 children with conditions unrelated to significant neurological disorders or musculoskeletal abnormalities that could affect gait biomechanics (n=17). Gait parameters were recorded using the Stedis trainer, which utilizes eight biometric sensors placed on the lower extremities — on the feet, lower third of the shins, upper third of the thighs, sacrum, and at the level of the 12th thoracic vertebra. Spatiotemporal and kinematic gait parameters were analyzed.
RESULTS: A comparative analysis was conducted between the two groups: the control group (children without significant neurological or musculoskeletal abnormalities affecting gait biomechanics) and the PsA group. Children with PsA demonstrated an increased stance phase duration and single-limb support time on the affected lower limb compared to the control group. The swing phase duration of the affected limb was reduced by approximately 1.5% compared to the healthy limb. The foot-lift height of the affected limb was found to be 5 cm higher than that of the healthy limb. Compared with the control group, single-limb support time for the healthy leg in control group children was nearly 4% higher than in children with PsA. The differences were statistically significant (р=0.009). The swing phase duration for the affected lower limb in children with PsA was 2.3% higher than in the control group. The differences were statistically significant (р=0.019). The overall swing phase duration was nearly 4% higher in the control group (р=0.019), with statistically significant differences. The differences were statistically significant (р=0.019).
CONCLUSION: The development of a gait pattern characteristic of PsA is determined by own mechanisms distinct from those in other types of arthritis.



Therapeutic physical factors as part of outpatient medical rehabilitation for patients after colorectal cancer surgery: а randomized controlled trial
Abstract
BACKGROUND: The comprehensive use of therapeutic physical factors in rehabilitation programs contributes to improving the effectiveness of therapeutic measures by favorably influencing sanogenesis processes.
AIM: To evaluate the effectiveness of an outpatient medical rehabilitation program for patients after colorectal cancer surgery using therapeutic physical factors.
MATERIALS AND METHODS: An open-label, randomized, controlled prospective study included 126 patients who underwent colorectal cancer surgery. Using simple randomization, the patients were divided into three groups. In Comparison group 1 (n=40), rehabilitation followed the Russian guidelines (individual therapeutic exercise and pinaverium bromide). In Comparison group 2 (n=43), in addition to the rehabilitation measures of Group 1, patients received low-mineralized mineral water “Psyz.” In the Main group (n=43), patients received transcutaneous electrical nerve stimulation in the area of the cervical sympathetic ganglia in addition to Group 2 rehabilitation program. The effectiveness of rehabilitation measures was assessed using clinical symptom evaluation based on the Edmonton Symptom Assessment System (ESAS) and quality of life assessment with the European Quality of Life Questionnaire (EQ-5D).
RESULTS: Statistical analysis demonstrated that incorporating therapeutic physical factors into outpatient medical rehabilitation programs for patients after colorectal cancer surgery significantly reduced clinical symptoms according to the ESAS scale (p <0.01) and improved quality of life indicators according to the EQ-5D scale, particularly in the Daily Activities (p <0.01), Pain and Discomfort (p < 0.01), and Anxiety and Depression (p <0.01) domains. Meanwhile, the positive changes in the studied parameters were, on average, 12–15% lower (p <0.05) in Comparison group 1 and 8–10% lower in Comparison group 2 compared with the Main group.
CONCLUSION: The inclusion of therapeutic physical factors in outpatient medical rehabilitation programs for patients after colorectal cancer surgery leads to a significant improvement in quality of life.



Results of indirect vibropercussion correction of the first cervical vertebra position in chronic subluxation
Abstract
BACKGROUND: Chronic subluxation of the first cervical vertebra (atlas) is a condition that remains insufficiently studied both in terms of diagnostic criteria and clinical outcomes of therapeutic interventions.
AIM: To evaluate the radiological and clinical outcomes of indirect instrumental correction of the C1 vertebra position using the Atlas-Standard protocol in patients with chronic pain syndrome.
Materials and METHODS: A single-center prospective study, AtlaStandard (ClinicalTrials.gov ID: NCT05986656), was conducted. Patients with chronic subluxation of the first cervical vertebra and lateral atlanto-dental interval asymmetry of ≥1 mm in at least one radiographic projection were consecutively enrolled. Indirect instrumental correction of the atlas position was performed using the Atlas-Standard technique with the ATLASPROF device. Follow-up radiography was scheduled one month after the intervention. Additionally, at six months, patients underwent a follow-up examination, physical assessment, survey, questionnaire-based evaluation, and spinal inclinometry.
RESULTS: The study included 46 participants — 14 men (30.4%) and 32 women (69.6%) — with a median age of 42 years (33; 49.8). After the intervention, a statistically significant reduction in lateral atlanto-dental interval asymmetry was observed in the anterior open-mouth projection and the posterior Fuchs projection, along with a decrease in the atlas tilt angle (p <٠.٠٥). Additionally, there was a significant reduction in the median tension headache intensity (measured by a numerical rating scale) and median pain levels across all spinal regions — cervical, thoracic, lumbar, and sacral (p <0.05). The use of analgesics decreased (p <0.001), functional disability scores on the Oswestry Disability Index 2.1a improved (p <0.05), and the vertical spinal axis deviation angle normalized in both the sagittal and frontal planes (p <0.05). No serious adverse events were recorded.
CONCLUSION: The Atlas-Standard technique using the ATLASPROF device enables indirect correction of the first cervical vertebra position in cases of chronic subluxation, as confirmed by radiographic data, with effects observed for at least one month post-procedure. Moreover, six months after treatment, this method demonstrates positive clinical outcomes, including reduced tension headache intensity, decreased pain in all spinal regions, reduced analgesic use, improved functional disability score, and normalization of spinal axis deviation angles.



Pyruvate-lactate reaction of the body to combined laser irradiation and transcanal electrophoresis of copper-calcium in patients with type 2 diabetes and periodontitis
Abstract
BACKGROUND: One of the pressing issues in modern medicine is diabetes mellitus (DM) and its comorbidities, including dental complications associated with it. The potential relationship between inflammatory processes in the oral cavity and the overall state of the body has been discussed for a long time, as DM alters the metabolic components of vital organ systems.
AIM. To improve the clinical effectiveness of dental treatment in patients with type 2 diabetes and periodontitis-periodontal disease by using transcanal copper-calcium electrophoresis and laser irradiation as adjunct therapies.
MATERIALS AND METHODS: A randomized, open-label clinical study was conducted involving 123 patients with type 2 diabetes and verified periodontitis. After obtaining informed consent, the oral cavity of all participants was examined, and additional radiological diagnostics were used to verify periodontitis-periodontal pathology. To assess the acid-base balance in the periodontal and periodontic tissues, the levels of pyruvate and lactate in the blood were measured using Lactate/Peruvat test kits (LOX-PAP, Biocom, Germany), along with blood glucose parameters (Express-Satellite-PKG-0.3 method) before and after combined treatment.
RESULTS: Significant shifts in baseline lactate levels were found in 75 (61.0%) patients, with lactate exceeding the physiological norm by 2.9 times (p < 0.05) and pyruvate levels below the physiological norm by 33.6% (p <0.01). After combined treatment, pyruvate levels increased and lactate levels decreased, leading to an improvement in the physiological ratio between lactate and pyruvate from 54.8 [51.7; 57.9] to 31.6 [30.7; 32.6] units (p <0.05), demonstrating correction of hypoxia and acid-base imbalance in the tissues.



Non-pharmacological technologies in rehabilitation programs for individuals with post-stress disorders
Abstract
AIM: To analyze the mechanisms and effectiveness of a rehabilitation program combining psychocorrection and transcutaneous electrical stimulation in individuals with post-stress disorders engaged in high-risk professions.
MATERIALS AND METHODS: The study included 120 men with repeated participation in combat operations, demonstrating high levels of stress. Within this group, two categories were identified (each comprising 60 individuals): active-duty personnel and veterans, further subdivided by age into those under 40 and those over 50 years old. The majority of men, particularly those in the older age group, exhibited the development of neuropsychiatric and somatic disorders of varying severity, with cardiovascular conditions being the most prevalent. Psychological and electrophysiological assessments supplemented the overall evaluation of participants’ health status. The practical aspect of the study initially compared the effectiveness of two types of psychorelaxation—autogenic training and breathing exercises—followed by an additional phase incorporating transcutaneous electrical stimulation.
RESULTS: The assessment of psychocorrection therapy demonstrated its greater effectiveness in middle-aged individuals. The achieved results were largely independent of the chosen psychological intervention method; however, in the older age group, breathing training proved to be more effective. Additionally, while psychorelaxation had a positive impact on the somatic health of middle-aged individuals, it was insufficiently effective for the older group. Given this, breathing training was supplemented with transcutaneous electrical stimulation, which significantly enhanced treatment outcomes.
CONCLUSION: This study confirms the effectiveness of the proposed rehabilitation program and underscores the potential for implementing new health restoration programs for socially significant populations.


