Vol 13, No 3 (2014)

The present paper is devoted to the assessment of the possibilities for the use of the concept of translational medicine in physical and rehabilitative medicine. A detailed description of the main directions of the development of translational medicine in physiotherapy and medical rehabilitation including personalized and evidence-based medicine and physioeconomics. Prospects for the further development of translational research in physiotherapy are outlined.

The present paper concerns the main approaches to the estimation of the effectiveness of the rehabilitative measures for the children presenting with functional disturbances in the locomotor system caused by retarded conversion of the primitive locomotor reflexes in the context of the long-term consequences of the craniocerebral injury. Diagnostics of these disturbances and dynamic observation of the children treated by various methods of manual therapy were carried out with the use of X-ray techniques, cardiointervalography, pulse-oxymetry, and bulbar conjuctiva biomicroscopy.

Thirty one puerperae at risk of developing infectious and inflammatory diseases (IID) following the abdominal delivery were divided into 2 groups for the investigation of the neurovegetative regulation of the organism by means of cardiointervalographic analysis on day 1 after surgery and on day 6 after daily intravenous laser irradiation of the blood (ILIB) or without this treatment. By way pf prophylaxis, all the women were given intravenous injections of antibiotic amoxiclav at a dose of 1.2 g 15 min before surgery. The study showed that the use of ILIB promoted normalization of the compromised compensatory and protective reactions and improved the functional reserves of the organism in 73.3% of the women which suggests the expediency of gthe inclusion of this procedure in the treatment of puerperae at risk of IID following the abdominal delivery. In the absence of ILIB, the neurovegetative regulation and the adaptive reactions recovered only in 43.7% of the cases.

Introduction. The break-up of erythrocytes and hemoglobin decomposition result in the release of indirect bilirubin that is possible detect in the blood. Indirect bilirubin is lipid-soluble, penetrates into the tissues (for example, into those of the central nervous system), and exhibits the histotoxic properties. Phototherapy is one of the methods by which the influence of bilirubin in the body can be reduced. Materials and methods. The newborn infants presenting with conjugational jaundice and included in this study were divided into 2 groups depending on their age. Those comprising groups IB and IIB were treated by phototherapy while the patients in groups IA and IIA served as controls. The direct to indirect bilirubin ratio (BR) at admission and upon discharge from the clinic was calculated alongside with the growth coefficient of direct and indirect bilirubin (GC), erythrocyte index, and hemoglobin content. Results. In control children of both age groups, the blood indirect bilirubin level decreased by 12 mcmol/day in contrast to the patients treated by phototherapy in whom it fell down much more rapidly (by 19-21 mcmol/ day; p < 0.001). Dynamics of decrease of the direct bilirubin level in the children of the younger age-group was virtually identical whereas it decreased more rapidly in the patients of the elder age-group (p < 0.05). Neither erythrocyte indices nor hemoglobin content were significantly different between the children treated by phytotherapy and the controls. It is hypothesized that the serum level of indirect bilirubin in these children is a result of immaturity of the hepatic glucuronyltransferase system. Conclusion. Phototherapy is an effective method for the treatment of newborn infants of different age presenting with conjugational jaundice.

We undertook a study designed to evaluate the effectiveness of peloid therapy with the use of salt-saturated silted therapeutic peloid from the lake Marmyshenskoye for the combined treatment of the patients, presenting with chronic pyelonephritis. We have analysed the results of the treatment of 48 patients. It was shown that the introduction of peloid therapy with the application of silted therapeutic peloid from the lake Marmyshenskoye in the combined treatment of the patients, presenting with chronic pyelonephritis more effectively than the standard treatment suppresses the inflammatory process due to the favourable influence on the urine microbial spectrum, decrease of leukocyturia level, acceleration of the recovery of homeostasis, activation of humoral immunity, and prevention of further chronization of the process.