Vol 19, No 1 (2020)

Background. The study of hormonal status in patients with erectile dysfunction (ED), especially the older and senior age groups, is most often limited to the evaluation of testosterone fractions

Aim: demonstrate the effectiveness of transcranial magnetotherapy in a combined treatment regimen for patients with «empty sella syndrome” (ESS).

Methods. Results of diagnostics examination and treatment of 118 patients with the ED hormonal form at the age of 23–57 are studied. The expressiveness of disturbances of erectile function and signs of androgenic deficiency are estimated by means of questionnaires of AMS and a scale of Morley, the penil color flow Doppler ultrasound with intracavernous pharmacological tests is carried out, the hormonal status is estimated. At suspicion of neuroendocrine pathology MRI of the brain is executed. At all examined patients signs of decrease erectile functions are revealed. In 62 (52.5%) observations during MRI the picture of ESS is revealed. In 22 (18.6%) observations the changes of an eyeground demonstrating increase in intracranial pressure takes place, however loss of fields of vision is not observed in any of patient. Persistent headaches are noted in 19 (16.1%) observations. In 46 (39%) observations at patients with considerable obesity signs of disturbance of tolerance to glucose and insulin resistance are revealed. To patients hormone replacement therapy is appointed, at identification of a hyperprolactinemia agonists of dopamine receptors in an individual dosage under control of level of prolactin are used, therapy of intracranial hypertensia is carried out. In complex therapy transcranial magnetotherapy is used.

Results. Therapy is effective, during treatment increase in frequency and duration of sexual intercourses is noted. At control Doppler researches of a penis improvement of a regional hemodynamics is noted. Cancellation of medicines lead to resuming of symptomatology of a disease.

Conclusion. Thus, the research shows powerful value of a syndrome of ESS in a pathogeny of ED demanding multidisciplinary approach with involvement of adjacent specialists — endocrinologists, neurologists and ophthalmologists. It is important to note that ESS, in most cases, is an accidental tomographic finding, at the same time often is followed by disturbance of tolerance to glucose, obesity, a metabolic syndrome. Introduction in complex therapy of transcranial magnetic influence substantially improves results of treatment of this category of patients, as due to additional stimulation of synthesis of pituitary hormones, and cerebral decompression.

Background. After operations on the ureter, it is important to use medical rehabilitation technologies aimed at preventing urodynamic disorders of the upper and lower urinary tract, stimulating reparative processes. In recent years, special attention has been drawn to high-intensity pulsed magnetotherapy, which has a more pronounced and long-lasting stimulating effect compared to other types of electrical stimulation.

Aim: to substantiate the feasibility of including high-intensity pulsed magnetic therapy in the comprehensive medical rehabilitation of children with hydronephrosis and concomitant neurogenic bladder dysfunction.

Methods. Clinical observations and special studies with the inclusion of high-intensity pulse magnetic therapy in the course of therapy were conducted in 100 children aged 4 to 15 years with hydronephrosis, a condition after surgery.

Results. Medical rehabilitation with the inclusion of high-intensity pulsed magnetic therapy had a positive effect on the urodynamics of the urinary tract, renal blood flow, helped to stop inflammation in the renal parenchyma and restore the rhythm of urination in children with hydronephrosis and concomitant neurogenic bladder dysfunction.

Conclusion. According to the research results, the feasibility of including high-intensity pulsed magnetic therapy in the complex of medical rehabilitation of children with hydronephrosis, concomitant neurogenic bladder dysfunction, is scientifically justified.

Background. The formation of scar tissue is a fairly physiological process, in most cases aimed at closing the skin defect in order to preserve the body’s homeostasis. Correction methods for atrophic scars include laser technology, radiofrequency therapy, injection methods and topical therapy.

Arm: the formation of scar tissue is a fairly physiological process, in most cases aimed at closing the skin defect in order to preserve the body’s homeostasis. Correction methods for atrophic scars include laser technology, radiofrequency therapy, injection methods and topical therapy.

Methods. There were 56 patients with atrophic scar. Depending on the therapeutic complex for the correction of аtrophic scar, 3 groups were formed: group 1 ― the combined use of RF-therapy for the pharmacophoresis of hyaluronic acid, group 2 ― radio frequency microneedle therapy, group 3 ― the pharmacophoresis of hyaluronic acid. In the work, the Dermatological Symptom Scale Index (DSSI), which was assessed before and after treatment, was adapted to evaluate clinical symptoms.

Results. In accordance with the total value of the DSSI, a more significant dynamics was observed in group 1, regardless of the type of AR (subgroups 1A and 1B). DSSI in the 1A subgroup decreased by 80.8% (p<0.01), in the 1B group by 82.4% (p<0.01). DSSI in the 2A subgroup decreased by 32.3% (p<0.01), in the 2B group by 61.4% (p<0.01). DSSI in the 3A subgroup decreased by 62.3% (p<0.01), in the 3B group by 33.7% (p<0.01). In group 1, where the combined treatment was carried out, a more pronounced efficacy was noted than when applying the components of the technique, which did not depend on the type of cicatricial deformity. In group 2, after the application of RF-therapy, the effectiveness was expressed to a much lesser extent, and the most significant results were obtained in patients with post-traumatic atrophic scars. In group 3, after a course of pharmacophoresis of a hyaluronic acid preparation, positive dynamics was observed to a greater extent with hormone-dependent scars.

Conclusions. The results of the study showed that the most effective method is the combined use of RF-therapy and the pharmacology of hyaluronic acid, at the same time with post-inflammatory (post-traumatic) atrophic scars, monotherapy with the use of radiofrequency microneedles is possible, with hormone-dependent atrophic scars, monotherapy of pharmacophoresis of hyaluronic acid is possible.

Background. Osteoarthritis is characterized by a decrease in the quality of life, which is currently considered as the main measure of well-being of an individual and a criterion for the effectiveness of treatment and rehabilitation measures. Modern research emphasizes the need for an integrated approach to the treatment of osteoarthritis, which should include pharmacological and non-drug methods of treatment.

Aim. The purpose of the study was to evaluate the effectiveness of pharmacopuncture administration of Alloplant biomaterial by patients with osteoarthritis of the knee joint from the standpoint of influencing the immunological mechanisms of the disease.

Methods. The randomization methodology was divided into 3 groups, comparable in terms of clinical and functional characteristics. Group I patients (n = 39) have standard basic drug therapy according to the federal clinical guidelines “Osteoarthritis” approved by the Association of Rheumatologists of Russia (2013), with additions from 2016; in patients of group II (n = 39), in addition to drug therapy, dispersed Alloplant biomaterial was used according to the original method; group III patients (n = 39) against the background of basic drug therapy are additionally prescribed a combination of dispersed Alloplant biomaterial at biologically active points and magnetic therapy with a pulsed magnetic field.

Results. Against the background of the treatment of patients with osteoarthritis using pharmacopuncture with Alloplant biomaterial and magnetotherapy, there was a positive dynamics in clinical data with a significant decrease in pain intensity when walking and at rest, stiffness, with the restoration of immune status parameters and an improvement in the quality of life in the field of physical and psychological health . A more pronounced and lasting positive dynamics was observed in patients of group III against the background of the combined effects of pharmacopuncture with Alloplant biomaterial and magnetotherapy.

Conclusion. The Alloplant biomaterial has a positive effect in the treatment of patients with stage I–II osteoarthritis according to the Kellgren–Lawrens classification. The similarity of the mechanism of action with drugs with a structurally modifying effect on cartilage allows us to recommend pharmacopuncture with Alloplant biomaterial for widespread use in the treatment of osteoarthritis.

In article the main achievements in a problem of studying of mechanisms of treatment-and-prophylactic use of drinking mineral waters are analysed. The important role of their nonspecific influence due to existence of a stressorny component, activation of digestive organs and increase in products of gastrointestpnalny and pancreatic hormones is proved. Increase in activity of enteroinsulyarny interrelations at intake of mineral waters provides optimization of the broken metabolic reactions. It is revealed that against the background of course intake of mineral waters the resistance to insulin due to optimization of hormonal and receptor interaction decreases. The role of activization of pro-oxidatic reactions in improvement of sensitivity of fabrics to insulin is discussed. Various methods of increase in medical potential of mineral waters due to change of algorithms of their use, enrichment are analyzed by vitamins and phytodrugs, nanoparticles of metals. The scheme of realization of biological potential of mineral water at its internal reception is offered.

In this article, we demonstrate a clinical case with high efficacy of Karipain electrophoresis in the treatment of a patient with discogenic radiculopathy in the cervical spine. The positive result was a complete regression of motor deficiency, restoration of sensory function and a decrease in the size of a hernia of the intervertebral disc at the level of C5–C6 by 40%.