Vol 9, No 6 (2010)

This work was designed to study characteristics of oxidative stress, anti-oxidative activity, and tissue hypoxia in 35 patients presenting with bronchial asthma complicated by chronic pulmonary heart disease. They were given basal therapy or its combination with ozonotherapy and administration of bishofite by electrophoresis. Analysis of the results of the combined treatment demonstrated positive dynamics of the ventilation-perfusion relationships in the lungs, the anti-oxidative system, and tissue hypoxia. The beneficial changes were especially pronounced in the group of patients managed by ozonotherapy; they were less apparent in patients treated with bishofite electrophoresis.

The authors report the development of a method for the enhancement of the efficacy of short-term courses of intensive combined treatment of patients presenting with ostoarthrosis by including intake of a succinic acid-containing preparation as a regulator of energy metabolism. It was shown that intensive (on a day-to-day basis) combined physio-, balneo-, and peloidotherapy along with regular intake of the succinate-based drug permitted to decrease the frequency of clinical manifestations of balneoresponsiveness, optimize the functional capacity of the main regulatory systems and energy production. These changes were associated with the increase of non-specific resistance of the organism and contributed to the reduction of severity or complete elimination of clinical symptoms of the disease within 14-16 days or much sooner than under effect of traditional therapy.

All the examined patients presenting with irritated bowel syndrome prevailed by the symptoms of constipation were shown to have intestinal dysbiosis associated with the abnormal metabolic activity of colonic microflora. Measurements of volatile fatty acids demonstrated a decrease in the absolute content of acetic, butyric, and valeric acids as well as reduction of the total content of intestinal metabolites. Combined rehabilitative treatment including local application of low-intensity bioresonant magnetotherapy on the colon projection region exerted positive effect on the metabolic activity of colonic microflora in patients with irritated bowel syndrome and the prevalence of constipation symptoms.

The chronic obstructive pulmonary disease was induced in white outbred rats exposed to cigarette smoke during 60 days. Analysis of the main plasma membrane phospholipid fractions in lymphocytes from peripheral blood revealed their abnormal content and ratio. Phototherapy using concentrated light pulses resulted in the apparent tendency toward normalization of membrane phospholipid levels within 30 days after the completion of 10 treatment sessions. It is concluded that the treatment byconcentrated pulses of light has beneficial effect on the content and ratio of main plasma membrane phospholipids in peripheral lymphocytes.

In the article the data about results of studying of the psycho-emotional status at patients lumbar-sacral radiculopathy is presented at application of structural-resonance therapy according to medical-psychological testing with use of the questionnaire "Cenesthesia. Activity. Mood". Besides, quality of the patients life included in research by means of questionnaire SF-36 has been studied. It has been established that application both general and local influences of structurally-resonant therapy raises quality of life as at patients with vertibralgenic, and neuropathic pains, selectively operating on various components of the general health.

The many-year experience with the use of low-power visible (VIS) and near-infrared (nIR) radiation of lasers, photodiodes, and other sources for medical purposes gives evidence of a large variety of its beneficial effects in humans and animals including anti-inflammatory, immunomodulating, wound-healing, and analgesic action. Nevertheless, certain clinicians (especially oncologists) appear unwilling to use these physiotherapeutic methods for fear of their stimulatory effect on the tumour growth and the development of metastases. Many are unaware that these phototherapeutic techniques are extensively used in the investigations with the use of experimental neoplasm models, e.g. in animals with transplanted malignant tumours. In the present paper, we summarize the relevant materials accumulated during the past 30 years and pertaining to the effect of the above forms of radiation on the neoplastic growth and the spread of metastases in laboratory animals after transplantation of different malignant tumours. The overwhelming majority of the studies indicate that VIS and nIR radiation applied in therapeutic doses normally used to promote wound healing in animals and humans slows down (rather than accelerates) the neoplastic growth rate and downregulates tumour dissemination. Moreover, both phototherapeutic modalities applied in combination with chemo- and radiotherapy tend to enhance their anti-tumourigenic efficacy.