Features of management and clinical course of the early rehabilitation period after acute coronary syndrome
- Authors: Gallamshin A.A.1, Mutallapov I.A.1, Matzhanova S.1, Babazhanova M.1, Mkhitaryan V.G.1, Umirov S.L.1, Tavlykaeva S.R.1, Davlatov M.D.1, Dubovik A.V.1, Makarova V.I.1, Rodionova A.S.1, Latypov A.R.1, Fatrahmanov R.R.2, Galimullina I.I.2
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Affiliations:
- Bashkir State Medical University
- Kazan State Medical University
- Issue: Vol 24, No 5 (2025)
- Pages: 332-347
- Section: Review
- Published: 01.06.2025
- URL: https://rjpbr.com/1681-3456/article/view/678789
- DOI: https://doi.org/10.17816/rjpbr678789
- EDN: https://elibrary.ru/sjylrv
- ID: 678789
Cite item
Abstract
Acute coronary syndrome remains one of the leading causes of mortality and disability worldwide, particularly in low- and middle-income countries. This review analyzes current approaches to cardiac rehabilitation in patients after acute coronary syndrome, with a focus on epidemiology, clinical features, and innovative strategies for cardiac rehabilitation programs. Key components of cardiac rehabilitation include physical activity, psychotherapeutic interventions, dietary therapy, and pharmacological treatment, all of which require a personalized approach to improve clinical outcomes. Special attention is given to gender differences in acute coronary syndrome progression and access to rehabilitation programs, as well as the impact of the COVID-19 pandemic on disease trends. Recent studies demonstrating the effectiveness of integrating digital technologies, telemedicine, and mobile applications into cardiac rehabilitation programs are reviewed. Both traditional rehabilitation methods and innovative approaches—including high-intensity interval training and the Mediterranean diet—are discussed, offering new perspectives for designing rehabilitation programs. Despite the proven effectiveness of cardiac rehabilitation, its implementation remains limited due to low patient adherence and insufficient accessibility in resource-limited regions. New clinical guidelines on optimizing rehabilitation strategies, aimed at reducing the risk of recurrent complications and improving patients’ quality of life, are currently under development.
Full Text
About the authors
Arslan A. Gallamshin
Bashkir State Medical University
Author for correspondence.
Email: formedkey@mail.ru
ORCID iD: 0009-0001-7788-6116
Russian Federation, Ufa
Iulai A. Mutallapov
Bashkir State Medical University
Email: 89871413659a@gmail.com
ORCID iD: 0009-0001-1116-6490
Russian Federation, Ufa
Shoira Matzhanova
Bashkir State Medical University
Email: matzanovasoira@gmail.com
ORCID iD: 0009-0006-6552-0471
Russian Federation, Ufa
Malika Babazhanova
Bashkir State Medical University
Email: babajanovamalika93@gmail.com
ORCID iD: 0009-0003-3704-9123
Russian Federation, Ufa
Victoria G. Mkhitaryan
Bashkir State Medical University
Email: viktoriagamletovna@mail.ru
Russian Federation, Ufa
Sayriddin L. Umirov
Bashkir State Medical University
Email: sairiddinumirov@gmail.com
ORCID iD: 0009-0008-8144-5875
Russian Federation, Ufa
Sabina R. Tavlykaeva
Bashkir State Medical University
Email: sabina.tavlykaeva@gmail.com
ORCID iD: 0009-0005-2144-1280
Russian Federation, Ufa
Mirzonazim D. Davlatov
Bashkir State Medical University
Email: mirzonozim2019@gmail.com
ORCID iD: 0009-0002-6912-9710
Russian Federation, Ufa
Angelina V. Dubovik
Bashkir State Medical University
Email: aswlz@yandex.ru
ORCID iD: 0009-0000-8893-2125
Russian Federation, Ufa
Veronika I. Makarova
Bashkir State Medical University
Email: Vm23eronika@gmail.com
ORCID iD: 0009-0002-0545-6798
Russian Federation, Ufa
Angelina S. Rodionova
Bashkir State Medical University
Email: Rodionovaangelina5320@gmail.com
ORCID iD: 0009-0002-5809-9608
Russian Federation, Ufa
Airat R. Latypov
Bashkir State Medical University
Email: Shazzam02@mail.ru
ORCID iD: 0009-0009-6401-8123
Russian Federation, Ufa
Rafil R. Fatrahmanov
Kazan State Medical University
Email: rafilfatrahmanov@gmail.com
ORCID iD: 0009-0007-7873-8557
Russian Federation, Kazan
Islamiya I. Galimullina
Kazan State Medical University
Email: Islamiya.galimullina.01@bk.ru
ORCID iD: 0009-0002-7804-1868
Russian Federation, Kazan
References
- Bergmark BA, Mathenge N, Merlini PA, et al. Acute coronary syndromes. Lancet. 2022;399(10332):1347–1358. doi: 10.1016/S0140-6736(21)02392-6
- Timmis A, Kazakiewicz D, Townsend N, et al. Global epidemiology of acute coronary syndromes. Nat Rev Cardiol. 2023;20(11):778–788. doi: 10.1038/s41569-023-00884-0
- Ralapanawa U, Sivakanesan R. Epidemiology and the magnitude of coronary artery disease and acute coronary syndrome: a narrative review. J Epidemiol Glob Health. 2021;11(2):169–177. doi: 10.2991/jegh.k.210525.001
- Cader FA, Banerjee S, Gulati M. Sex differences in acute coronary syndromes: a global perspective. J Cardiovasc Dev Dis. 2022;9(8):239. doi: 10.3390/jcdd9080239
- Tolentino Júnior DS, De Assis EM, De Oliveira RC. Diagnostic and Therapeutic Resources for Risk Stratification of Patients With Acute Coronary Syndrome. Hosp Pract Res. 2021;6(1):1–6. doi: 10.34172/hpr.2021.01
- Damluji AA, Forman DE, Wang TY, et al. Management of acute coronary syndrome in the older adult population: a scientific statement from the American Heart Association. Circulation. 2023;147(3):e32–e62. doi: 10.1161/CIR.0000000000001118
- Gorog DA, Ferreiro JL, Ahrens I, et al. De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis. Nat Rev Cardiol. 2023;20(12): 830–844. doi: 10.1038/s41569-023-00900-3
- Gadager BB, Tang LH, Ravn MB, et al. Benefits of cardiac rehabilitation following acute coronary syndrome for patients with and without diabetes: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2022;22(1):295. doi: 10.1186/s12872-022-02734-2
- Thakker R, Khan M, Al-Hemyari B. Cardiac rehabilitation after hospitalization for acute coronary syndrome. Curr Cardiol Rep. 2023;25(12):1699–1703. doi: 10.1007/s11886-023-01980-w
- Ishihara K, Izawa KP, Kitamura M, et al. Effects of cardiac rehabilitation on cognitive function in patients with acute coronary syndrome: A systematic review. Heliyon. 2024;10:e24653. doi: 10.1016/j.heliyon.2024.e24653
- Redfern J, Gallagher R, O’Neil A, et al. Historical context of cardiac rehabilitation: learning from the past to move to the future. Front Cardiovasc Med. 2022;9:842567. doi: 10.3389/fcvm.2022.842567
- Erlikh AD, Zilov AV, Shchekochikhin DYu, et al. Brief review of the 2023 European Society of Cardiology guidelines for the management of cardiovascular diseases in patients with diabetes mellitus. Problemy Endokrinologii. 2024;70(4):94–102. doi: 10.14341/probl13414. EDN: ELKMTS
- Ulitina AS, Sirotkina OV, Vershinina EG, et al. Pharmacogenetics of acute coronary syndrome: the role of single nucleotide polymorphisms (literature review). Rossiyskiy Zhurnal Personalizirovannoy Meditsiny. 2024;4(4):295–312. doi: 10.18705/2782-3806-2024-4-4-295-312. EDN: HOTCAX
- Biktashev DB, Zhukusheva ShT, Akhmetova ZhB, et al. New syndromes and patterns of acute coronary artery occlusion. Literature review. Science. 2023;25(6):171–180. doi: 10.34689/SH.2023.25.6.020. EDN: GWYWZI
- Mustafina MO, Telzhanov A, Ligai ZN. Cardiovascular pathology: prevalence, risk factors (literature review). Vestnik Kazakhskogo Natsional'nogo Meditsinskogo Universiteta. 2021;(2):84–92. EDN: OKVNBZ
- Chaulin AM. Gender differences in serum cardiac troponin levels and their diagnostic significance in acute coronary syndrome (literature review). Laboratornaya Diagnostika. Vostochnaya Evropa. 2022;11(3):323–338. doi: 10.34883/PI.2022.11.3.008 EDN: XZOMQK
- Petrova MM, Afanasyeva DS, Kononova AS, et al. The impact of frailty syndrome on cardiovascular diseases (literature review). Sibirskoe Meditsinskoe Obozrenie. 2024;147(3):12–20. doi: 10.20333/25000136-2024-3-12-20 EDN: PXXQIB
- Filimonova AA, Shurpo EM, Kotlyarov SN, et al. Acute myocardial injury in COVID-19: types, mechanisms, diagnostic criteria, and prognosis. Nauka Molodykh — Eruditio Juvenium. 2022;10(3):311–326. doi: 10.23888/HMJ2022103311-326 EDN: BUQIAK
- Vakhnenko YuV, Korotkikh AV, Bagdasaryan EA. Myocardial injury in novel coronavirus infection (literature review). Byulleten' Fiziologii i Patologii Dykhaniya. 2021;(82):129–145. doi: 10.36604/1998-5029-2021-82-129-145 EDN: LAROVM
- Tugutov RV, Dashibalova TL. Clinical and angiographic features of acute coronary syndrome in patients over 80 years old in the Republic of Buryatia. Bulletin of the Buryat State University. Medicine and Pharmacy. 2023;(1):32–42. doi: 10.18101/2306-1995-2023-1-32-42 EDN: GUGVAU
- Karetnikova VN, Neeshpapa AG, Peanova KhA. Traditional and non-traditional risk factors for myocardial infarction in young adults. Russian Medical Inquiry. 2024;8(1):26–30. doi: 10.32364/2587-6821-2024-8-1-4 EDN: ERPROJ
- Nesova AK, Tsydypova DB, Ryabov VV. Clinical profile of patients with non-ST-segment elevation acute coronary syndrome: experience of a regional vascular center. Kardiovaskulyarnaya Terapiya i Profilaktika. 2024;23(8):34–44. doi: 10.15829/1728-8800-2024-3994 EDN: DJOGIQ
- Boytsov SA, Provatorov S. Opportunities for improving in-hospital and long-term prognosis in unstable angina. Terapevticheskiy Arkhiv. 2024;96(1):5–10. doi: 10.26442/00403660.2024.01.202555. EDN: CFLVTD
- Ullah A, Kumar M, Sayyar M, et al. Revolutionizing cardiac care: a comprehensive narrative review of cardiac rehabilitation and the evolution of cardiovascular medicine. Cureus. 2023;15(10):e46469. doi: 10.7759/cureus.46469
- Vilela EM, Ladeiras-Lopes R, Joao A, et al. Current role and future perspectives of cardiac rehabilitation in coronary heart disease. World J Cardiol. 2021;13(12):695–709. doi: 10.4330/wjc.v13.i12.695
- Zaree A, Dev S, Khan IY, et al. Cardiac rehabilitation in the modern era: optimizing recovery and reducing recurrence. Cureus. 2023;15(9):e46006. doi: 10.7759/cureus.46006
- Thomas RJ, Beatty AL, Beckie TM, et al. Home-based cardiac rehabilitation: a scientific statement from the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology. Circulation. 2019;140(1):e69–e89. doi: 10.1161/CIR.0000000000000663
- Passantino A, Dalla Vecchia LA, Corrà U, et al. The future of exercise-based cardiac rehabilitation for patients with heart failure. Front Cardiovasc Med. 2021;8:709898. doi: 10.3389/fcvm.2021.709898
- Dibben GO, Faulkner J, Oldridge N, et al. Exercise-based cardiac rehabilitation for coronary heart disease: a meta-analysis. Eur Heart J. 2023;44(6):452–469. doi: 10.1093/eurheartj/ehac747
- Zhang S, Lin Y. Advancements, challenges, and innovative strategies in cardiac rehabilitation for patients with acute myocardial infarction: A systematic review. Curr Probl Cardiol. 2024:102934. doi: 10.1016/j.cpcardiol.2024.102934
- Ben-Tzur D, Sabovich S, Hutzler Y, et al. Advances in Technology Promote Patient-Centered Care in Cardiac Rehabilitation. Cardiol Rev. 2025;33(2):160–165. doi: 10.1097/CRD.0000000000000599
- Gallagher R, Woolaston A, Tofler G, et al. Cognitive impairment and psychological state in acute coronary syndrome patients: A prospective descriptive study at cardiac rehabilitation entry, completion and follow-up. Eur J Cardiovasc Nurs. 2021;20(1):56–63. doi: 10.1177/1474515120963843
- Serrano-Rosa MÁ, León-Zarceño E, Giglio C, et al. Psychological state after an acute coronary syndrome: impact of physical limitations. Int J Environ Res Public Health. 2021;18(12):6473. doi: 10.3390/ijerph18126473
- Chen X, Zeng M, Chen C, et al. Efficacy of psycho-cardiology therapy in patients with acute myocardial infarction complicated with mild anxiety and depression. Front Cardiovasc Med. 2023;9:1031255. doi: 10.3389/fcvm.2022.1031255
- Ryan EM, Creaven AM, Ní Néill E, et al. Anxiety following myocardial infarction: A systematic review of psychological interventions. Health Psychol. 2022;41(9):599–610. doi: 10.1037/hea0001188
- Huang C. Effect of new cardiac rehabilitation mode on cardiac function, mental state and quality of life of postoperative patients with acute myocardial infarction treated with atorvastatin calcium tablet. Eur Rev Med Pharmacol Sci. 2023;27(8):3428–3436. doi: 10.26355/eurrev_202304_32145
- Ren Y, Tang H, Zhang L, et al. Exploration of therapeutic models for psycho-cardiology: From cardiac to psychological rehabilitation. Heliyon. 2024;10(1):e24012. doi: 10.1016/j.heliyon.2024.e24012
- Bertolín-Boronat C, Marcos-Garcés V, Merenciano-González H, et al. Depression, Anxiety, and Quality of Life in a Cardiac Rehabilitation Program Without Dedicated Mental Health Resources Post-Myocardial Infarction. J Cardiovasc Dev Dis. 2025;12(3):92. doi: 10.3390/jcdd12030092
- Wrzeciono A, Mazurek J, Cieślik B, et al. Psychologically-enhanced cardiac rehabilitation for psychological and functional improvement in patients with cardiovascular disease: a systematic review with meta-analysis and future research directions. Physiotherapy. 2024;122:45–56. doi: 10.1016/j.physio.2023.12.003
- Princip M, Pazhenkottil AP, Barth J, et al. Effect of Early Psychological Counseling for the Prevention of Posttraumatic Stress Induced by Acute Coronary Syndrome at Long-Term Follow-Up. Front Psychiatry. 2022;13:846397. doi: 10.3389/fpsyt.2022.846397
- Khan Z, Musa K, Abumedian M, et al. Prevalence of depression in patients with post-acute coronary syndrome and the role of cardiac rehabilitation in reducing the risk of depression: a systematic review. Cureus. 2021;13(12):e20678. doi: 10.7759/cureus.20678
- Miao X, Jiang H, Huang X, et al. Randomized trial of early exercise rehabilitation and its effects on patients with acute coronary syndrome. Sci Rep. 2024;14(1):26289. doi: 10.1038/s41598-024-56293-x
- Yu H, Yang H. Effect of early home-based exercise for cardiac rehabilitation on the prognosis of patients with acute myocardial infarction after percutaneous coronary intervention. Am J Transl Res. 2021;13(7):7839–7847.
- Liu X, Zou Y, Huang D, et al. Effect of evidence-based nursing combined with exercise rehabilitation in patients with acute myocardial infarction after percutaneous coronary intervention. Am J Transl Res. 2022;14(10):7424–7433.
- D’Andrea A, Carbone A, Ilardi F, et al. Effects of high intensity interval training rehabilitation protocol after an acute coronary syndrome on myocardial work and atrial strain. Medicina. 2022;58(3):453. doi: 10.3390/medicina58030453
- Kovalchuk Y, Tereshchenko N, Shumakov V, et al. The assessment of the impact of physical exercise level on the quantity of endothelial cell precursor progenitor cells in patients after ACS on the background of cardiac rehabilitation measures. Eur J Prev Cardiol. 2024;31(Suppl_1):zwae175–414. doi: 10.1093/eurjpc/zwae175.414
- Babii LM, Shumakov VO, Pohurelska OP, et al. Clinical, instrumental and biochemical associations of the degree of physical recovery in patients suffered from acute coronary syndrome at the completion of in-hospital rehabilitation period. J Med Life. 2023;76(10):2135–2142.
- Hu Q, Li PX, Li YS, et al. Daily exercise improves the long-term prognosis of patients with acute coronary syndrome. Front Public Health. 2023;11:1126413. doi: 10.3389/fpubh.2023.1126413
- McHale S. The influence of perceived levels of physical activity on engagement with cardiac rehabilitation after acute coronary syndrome [doctoral dissertation]. University of Dublin; 2022.
- Hollings M, Zhao E, Weddell J, et al. Lower cardiac rehabilitation enrolment occurs in acute coronary syndrome patients who report low levels of physical activity at four weeks post-event: A prospective observational study using physical activity tracker data. Heart Lung. 2024;64:143–148. doi: 10.1016/j.hrtlng.2023.11.003
- Melhem NJ, Taleb S. Tryptophan: from diet to cardiovascular diseases. Int J Mol Sci. 2021;22(18):9904. doi: 10.3390/ijms22189904
- Laffond A, Rivera-Picón C, Rodríguez-Muñoz PM, et al. Mediterranean diet for primary and secondary prevention of cardiovascular disease and mortality: an updated systematic review. Nutrients. 2023;15(15):3356. doi: 10.3390/nu15153356
- Raj P, Thandapilly SJ, Wigle J, et al. A comprehensive analysis of the efficacy of resveratrol in atherosclerotic cardiovascular disease, myocardial infarction and heart failure. Molecules. 2021;26(21):6600. doi: 10.3390/molecules26216600
- Karam G, Agarwal A, Sadeghirad B, et al. Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis. BMJ. 2023;380:e072003. doi: 10.1136/bmj-2022-072003
- Delgado-Lista J, Alcala-Diaz JF, Torres-Peña JD, et al. Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial. Lancet. 2022;399(10338):1876–1885. doi: 10.1016/S0140-6736(22)00122-2
- Novaković M, Rajkovič U, Košuta D, et al. Effects of cardiac rehabilitation and diet counselling on adherence to the Mediterranean lifestyle in patients after myocardial infarction. Nutrients. 2022;14(19):4048. doi: 10.3390/nu14194048
- Szczepańska E, Białek-Dratwa A, Janota B, Kowalski O. Dietary therapy in prevention of cardiovascular disease (CVD) — tradition or modernity? A review of the latest approaches to nutrition in CVD. Nutrients. 2022;14(13):2649. doi: 10.3390/nu14132649
- Nestel PJ, Mori TA. Dietary patterns, dietary nutrients and cardiovascular disease. Rev Cardiovasc Med. 2022;23(1):17. doi: 10.31083/j.rcm2301017
- Bhatt DL, Lopes RD, Harrington RA. Diagnosis and treatment of acute coronary syndromes: a review. JAMA. 2022;327(7):662–675. doi: 10.1001/jama.2022.0358
- Kamran H, Jneid H, Kayani WT, et al. Oral antiplatelet therapy after acute coronary syndrome: a review. JAMA. 2021;325(15):1545–1555. doi: 10.1001/jama.2021.0716
- Ge Z, Kan J, Gao X, et al. Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT): a randomised, placebo-controlled, double-blind clinical trial. Lancet. 2024;403(10439):1866–1878. doi: 10.1016/S0140-6736(24)00473-2
- Blacher J, Olié V, Gabet A, et al. Two-year prognosis and cardiovascular disease prevention after acute coronary syndrome: the role of cardiac rehabilitation — a French nationwide study. Eur J Prev Cardiol. 2024;31(16):1939–1947. doi: 10.1093/eurjpc/zwad365
- Soldati S, Di Martino M, Rosa AC, et al. The impact of in-hospital cardiac rehabilitation program on medication adherence and clinical outcomes in patients with acute myocardial infarction in the Lazio region of Italy. BMC Cardiovasc Disord. 2021;21:1–13. doi: 10.1186/s12872-021-02249-2
- Kanaoka K, Iwanaga Y, Nakai M, et al. Outpatient cardiac rehabilitation dose after acute coronary syndrome in a nationwide cohort. Heart. 2023;109(1):40–46. doi: 10.1136/heartjnl-2022-321639
- Steen DL, Khan I, Andrade K, et al. Event rates and risk factors for recurrent cardiovascular events and mortality in a contemporary post acute coronary syndrome population representing 239 234 patients during 2005 to 2018 in the United States. J Am Heart Assoc. 2022;11(9):e022198. doi: 10.1161/JAHA.121.022198
- Yudi MB, Clark DJ, Tsang D, et al. SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes: a randomized controlled trial. Coron Artery Dis. 2021;32(5):432–440. doi: 10.1097/MCA.0000000000000987
- Lee CY, Liu KT, Lu HT, et al. Sex and gender differences in presentation, treatment and outcomes in acute coronary syndrome, a 10 year study from a multi-ethnic Asian population: The Malaysian National Cardiovascular Disease Database — Acute Coronary Syndrome (NCVD-ACS) registry. PLoS One. 2021;16(2):e0246474. doi: 10.1371/journal.pone.0246474
- Hyun K, Negrone A, Redfern J, et al. Gender difference in secondary prevention of cardiovascular disease and outcomes following the survival of acute coronary syndrome. Heart Lung Circ. 2021;30(1): 121–127. doi: 10.1016/j.hlc.2020.06.024
- Toscano O, Cosentino N, Campodonico J, et al. Acute myocardial infarction during the COVID-19 pandemic: an update on clinical characteristics and outcomes. Front Cardiovasc Med. 2021;8:648290. doi: 10.3389/fcvm.2021.648290
- Su S, Zhao Y, Zeng N, et al. Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update. Mol Psychiatry. 2023;28(10):4056–4069. doi: 10.1038/s41380-023-02171-3
- Chew DP, Hyun K, Morton E, et al. Objective risk assessment vs standard care for acute coronary syndromes: a randomized clinical trial. JAMA Cardiol. 2021;6(3):304–313. doi: 10.1001/jamacardio.2020.6314
- Picano E, Pierard L, Peteiro J, et al. The clinical use of stress echocardiography in chronic coronary syndromes and beyond coronary artery disease: a clinical consensus statement from the European Association of Cardiovascular Imaging of the ESC. Eur Heart J Cardiovasc Imaging. 2024;25(2):e65–e90. doi: 10.1093/ehjci/jead306
- Raza A. Management of Acute Coronary Syndromes: Best Practices and Evolving Strategies. Pak J Med Cardiol Rev. 2023;1(2):9–30.
- Bansal A, Hiwale K. Updates in the management of coronary artery disease: a review article. Cureus. 2023;15(12):e50015. doi: 10.7759/cureus.50015
- Sayutina EV, Osadchuk MA, Romanov BK, et al. Cardiac rehabilitation and secondary prevention after acute myocardial infarction: a modern perspective. Russ Med J. 2021;27(6):571–587. doi: 10.17816/0869-2106-2021-27-6-571-587 EDN: GWLGGP
- Mixmonalieva NU, Nuritdinova SK. Features of physical rehabilitation and quality of life in patients with ischemic heart disease who underwent percutaneous coronary intervention. Multidiscip J Sci Technol. 2025;5(1):296–302.
- Manzoor S, Hisam A, Aziz S, et al. Effectiveness of mobile health augmented cardiac rehabilitation on behavioural outcomes among post-acute coronary syndrome patients: a randomised controlled trial. J Coll Physicians Surg Pak. 2021;31(10):1148–1153. doi: 10.29271/jcpsp.2021.10.1148
- Liu H, Zhang H, Qin Y, et al. Study on out-of-hospital management mode of patients with acute coronary syndrome after PCI in rural areas. Int Heart J. 2022;63(6):1026–1033. doi: 10.1536/ihj.22-046
- Cai H, Cao P, Zhou W, et al. Effect of early cardiac rehabilitation on prognosis in patients with heart failure following acute myocardial infarction. BMC Sports Sci Med Rehabil. 2021;13:1–13. doi: 10.1186/s13102-021-00352-7
- Wang B, Li J, Hong Y, et al. Effect of cardiac rehabilitation therapy combined with WeChat platform education on patients with unstable angina pectoris after PCI. J Healthc Eng. 2022;2022:7253631. doi: 10.1155/2022/7253631
- Zhu T, Liu H, Han A, et al. Orem’s self-care to treat acute coronary syndrome after PCI helps improve rehabilitation efficacy and quality of life. Am J Transl Res. 2021;13(4):2752–2761.
- Damluji AA, Forman DE, Wang TY, et al. Management of acute coronary syndrome in the older adult population: a scientific statement from the American Heart Association. Circulation. 2023;147(3):e32–e62. doi: 10.1161/CIR.0000000000001112
- Ambrosetti M, Abreu A, Corrà U, et al. Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology. Eur J Prev Cardiol. 2021;28(5):460–495. doi: 10.1177/2047487320913379
- Beatty AL, Beckie TM, Dodson J, et al. A new era in cardiac rehabilitation delivery: research gaps, questions, strategies, and priorities. Circulation. 2023;147(3):254-266. doi: 10.1161/CIRCULATIONAHA.122.061046.
- Zorina O, Fatkulina N, Saduyeva F, et al. Patient adherence to therapy after myocardial infarction: A scoping review. Patient Prefer Adherence. 2022;16:1613–1622. doi: 10.2147/PPA.S370221
- Winnige P, Vysoky R, Dosbaba F, et al. Cardiac rehabilitation and its essential role in the secondary prevention of cardiovascular diseases. World J Clin Cases. 2021;9(8):1761–1774. doi: 10.12998/wjcc.v9.i8.1761
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