Dynamics of clinical and functional indicators in patients with the consequences of combined facial skin trauma during the implementation of comprehensive rehabilitation programs



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Rationale: Combined facial skin trauma (CFST) often leads to scars and traumatic tattooing, causing substantial cosmetic and psychological distress. Effective evidence-based rehabilitation strategies are lacking due to a scarcity of controlled studies.

Objective: This study aimed to assess changes in clinical, functional, psychophysiological, and quality of life (QoL) outcomes in patients with CFST sequelae following comprehensive rehabilitation.

Materials and Methods: A prospective randomized comparative trial was conducted involving patients with CFST sequelae. Participants were randomized into two groups: the study group received combined rehabilitation using laser technologies and carboxytherapy, while the control group received standard care (facial massage, phonophoresis with lidase, and methyluracil ointment).

Primary endpoints included scar and pigment severity scores. Secondary endpoints comprised instrumental skin measurements, psychophysiological parameters, and QoL assessments. The rehabilitation program duration was 4 months per patient.

Results:
All 71 enrolled patients completed the study without adverse events.

The study group demonstrated significantly greater improvement in rehabilitation effectiveness (p<0.001) compared to the control group.

Tissue stiffness was significantly lower in the study group (median=25.3 kPa) than in the control group (median=30.9 kPa; p<0.05). The intervention group also showed significantly better outcomes in skin texture, surface morphometry, pigment levels, hemoglobin concentration, and lymph flow.

Psychophysiological parameters improved significantly only in the study group. QoL assessments using the WHOQOL-100 questionnaire confirmed superior outcomes in the intervention group.

Conclusion: The comprehensive rehabilitation approach incorporating high-intensity laser therapy and carboxytherapy proves significantly more effective than standard therapy for managing CFST sequelae, improving both physiological and psychological outcomes.

 

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作者简介

Natalia Shanina

Военно-медицинская Академия им С.М. Кирова

编辑信件的主要联系方式.
Email: shanina_n@mail.ru
ORCID iD: 0000-0002-0254-7048

заведующий лазерным отделением ККВБ

俄罗斯联邦

Alexander Patrushev

Email: alexpat2@yandex.ru

Denis Kovlen

S.M. Kirov Military Medical Academy, Saint Petersburg, Russia

Email: denis.kovlen@mail.ru
俄罗斯联邦, Rossia, 194044, SPb, st.Botkinskaya 21 «1»

参考

  1. Paasch, U., Zidane, M., Baron, J. M., & et al. (2022). S2k guideline: Laser therapy of the skin. Journal of the German Society of Dermatology (JDDG), 20(9), 1248–1267. https://doi.org/10.1111/ddg.14879
  2. Kurniadi, I., Tabri, F., Madjid, A., & et al. (2021). Laser tattoo removal: fundamental principles and practical approach. Dermatologic Therapy, 34(1), e14418. https://doi.org/10.1111/dth.14418
  3. Bonan, P., Bassi, A., Bruscino, N., & et al. (2019). Combined pulsed dye laser and Q-switched Nd:YAG laser in traumatic facial tattoo removal: a case series. Dermatologic Therapy, 32(5), e13069. https://doi.org/10.1111/dth.13069
  4. Yang, Q., Xue, P., Fan, X., & et al. (2022). Lasers treatment for traumatic facial tattoo. Lasers in Medical Science, 38(1), 28. https://doi.org/10.1007/s10103-022-03658-1
  5. Kozlovsky, V. L., & Maslovsky, S. Yu. (2011). Guidelines for assessing the quality of life in patients with schizophrenia during maintenance therapy. St. Petersburg: V.M. Bekhterev St. Petersburg Psychoneurological Research Institute. Retrieved May 24, 2025, from http://nmic.bekhterev.ru/upload/documents/2011_08.pdf (in Russian).
  6. Shanina, N. A., Patrushev, A. V., Yurchenko, K. S., & Khomyakova, S. V. (2025, February 3). Method for removing traumatic impregnation in a scar (Russian Federation Patent No. 2834147). Bulletin No. 4. Retrieved June 29, 2025, from https://patentimages.storage.googleapis.com/f7/b3/c0/8ca8d33b01c4e3/RU2834147C1.pdf (in Russian).
  7. Safonova, T. N., Kintyukhina, N. P., Sidorov, V. V., Gladkova, O. V., & Rein, E. S. (2017). Microcirculatory blood and lymph flow examination in eyelid skin by laser Doppler flowmetry. Annals of Ophthalmology, (3), 16–21. https://doi.org/10.17116/oftalma2017133316-21 (in Russian).
  8. Orlov, L. V. (2002). Laser Doppler flowmetry in medical practice. Kazan Medical Journal, 83(3), 217–218 (in Russian).
  9. Sullivan, T., Smith, J., Kermode, J., McIver, E., & Courtemanche, D. J. (1990). Rating the burn scar. Journal of Burn Care & Rehabilitation, 11(3), 256–260. https://doi.org/10.1097/00004630-199005000-00014
  10. Draaijers, L. J., Tempelman, F. R., Botman, Y. A., Tuinebreijer, W. E., Middelkoop, E., Kreis, R. W., & van Zuijlen, P. P. (2004). The Patient and Observer Scar Assessment Scale: a reliable and feasible tool for scar evaluation. Plastic and Reconstructive Surgery, 113(7), 1960–1965. https://doi.org/10.1097/01.PRS.0000122207.28773.56
  11. Singer, A. J., Arora, B., Dagum, A., Valentine, S., & Hollander, J. E. (2007). Development and validation of a novel scar evaluation scale. Plastic and Reconstructive Surgery, 120(7), 1892–1897. https://doi.org/10.1097/01.prs.0000287275.15511.10
  12. Shamrey, V. K., & Marchenko, A. A. (Eds.). (2023). Psychiatry: a textbook. SpetsLit (in Russian).
  13. Gurnani, P., Williams, N., Al-Hetheli, G., & et al. (2022). Comparing the efficacy and safety of laser treatments in tattoo removal: a systematic review. Journal of the American Academy of Dermatology, 87(1), 103–109. https://doi.org/10.1016/j.jaad.2020.07.117
  14. Hernandez, L., Mohsin, N., Frech, F. S., & et al. (2022). Laser tattoo removal: laser principles and an updated guide for clinicians. Lasers in Medical Science, 37(6), 2581–2587. https://doi.org/10.1007/s10103-022-03576-2
  15. Fusade, T., Toubel, G., Grognard, C., & Mazer, J. M. (2000). Treatment of gunpowder traumatic tattoo by Q-switched Nd:YAG laser: an unusual adverse effect. Dermatologic Surgery, 26(11), 1057–1059. https://doi.org/10.1046/j.1524-4725.2000.0260111057.x
  16. Shanina, N. A., Patrushev, A. V., & Makhonya, D. A. (2020). Treatment of facial traumatic tattoo. Aesthetic Medicine, 19(1), 71–73 (in Russian)

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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