The results of the use of preformed physical factors in the rehabilitation treatment of corneal ulcers

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BACKGROUND: Currently, an infectious corneal ulcer, a defect in the corneal epithelium, remains one of the main causes of monocular blindness, which necessitates the development of new effective methods of treatment.

AIMS: The aim of the study is to develop and evaluate the effectiveness of a methodology for the complex application of preformed physical factors of local and segmental action in patients with corneal ulcers.

MATERIALS AND METHODS: The study involved 85 patients with corneal ulcer defect aged 18 to 60 years, who were divided into three groups. Patients of the control group (29 people) received standard drug therapy, the comparison group (29 people) underwent a course of magnetophoresis with solcoseryl on closed eyelids against the background of standard drug therapy, patients of the main group (27 people) received standard drug therapy. magnetophoresis and low-frequency electrostatic fields on the collar area. All patients were assessed for visual acuity, the size of the ulcer and the area of stromal infiltration. The subjective severity of pain syndrome (VAS scale), psychoemotional state (SAN test) were assessed.

RESULTS: Immediately after treatment, visual acuity in the main group was significantly higher than in the comparison group and the control group, and averaged 0.14±0.14. The size of the ulcerative defect in the main group was significantly smaller than in the control group and the comparison group (p <0.05). The assessment of the psychoemotional state of patients after treatment revealed significant differences in the main group in relation to the control group on the Well-Being scale (p <0.05).

CONCLUSION: The use of preformed physical factors in the form of a course application of a low-frequency electrostatic field and magnetophoresis with the drug Solcoseryl made it possible to shorten the time of epithelialization of the ulcer and suppression of the inflammatory reaction in the cornea, which made it possible to significantly improve the clinical and functional parameters of the eye, as well as reduce the severity of pain syndrome against the background of an improvement in the psycho-emotional state patients.

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About the authors

Olga V. Yurova

National Medical Research Center for Rehabilitation and Balneology

Author for correspondence.
ORCID iD: 0000-0001-7626-5521
SPIN-code: 9577-7593

Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Yaroslav A. Solovyov

City Clinical Hospital № 1 of the Moscow Healthcare Department

ORCID iD: 0000-0002-9550-7175
Russian Federation, Moscow

Tatiana V. Konchugova

National Medical Research Center for Rehabilitation and Balneology

ORCID iD: 0000-0003-0991-8988
SPIN-code: 3198-9797

Dr. Sci. (Med.), Professor

Russian Federation, Moscow


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