The results of the use of preformed physical factors in the rehabilitation treatment of corneal ulcers

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

BACKGROUND: Currently, an infectious corneal ulcer, a defect in the corneal epithelium, remains one of the main causes of monocular blindness, which necessitates the development of new effective methods of treatment.

AIMS: The aim of the study is to develop and evaluate the effectiveness of a methodology for the complex application of preformed physical factors of local and segmental action in patients with corneal ulcers.

MATERIALS AND METHODS: The study involved 85 patients with corneal ulcer defect aged 18 to 60 years, who were divided into three groups. Patients of the control group (29 people) received standard drug therapy, the comparison group (29 people) underwent a course of magnetophoresis with solcoseryl on closed eyelids against the background of standard drug therapy, patients of the main group (27 people) received standard drug therapy. magnetophoresis and low-frequency electrostatic fields on the collar area. All patients were assessed for visual acuity, the size of the ulcer and the area of stromal infiltration. The subjective severity of pain syndrome (VAS scale), psychoemotional state (SAN test) were assessed.

RESULTS: Immediately after treatment, visual acuity in the main group was significantly higher than in the comparison group and the control group, and averaged 0.14±0.14. The size of the ulcerative defect in the main group was significantly smaller than in the control group and the comparison group (p <0.05). The assessment of the psychoemotional state of patients after treatment revealed significant differences in the main group in relation to the control group on the Well-Being scale (p <0.05).

CONCLUSION: The use of preformed physical factors in the form of a course application of a low-frequency electrostatic field and magnetophoresis with the drug Solcoseryl made it possible to shorten the time of epithelialization of the ulcer and suppression of the inflammatory reaction in the cornea, which made it possible to significantly improve the clinical and functional parameters of the eye, as well as reduce the severity of pain syndrome against the background of an improvement in the psycho-emotional state patients.

Full Text

Restricted Access

About the authors

Olga V. Yurova

National Medical Research Center for Rehabilitation and Balneology

Author for correspondence.
Email: yurovaov@nmicrk.ru
ORCID iD: 0000-0001-7626-5521
SPIN-code: 9577-7593

Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Yaroslav A. Solovyov

City Clinical Hospital № 1 of the Moscow Healthcare Department

Email: yurovaov@nmicrk.ru
ORCID iD: 0000-0002-9550-7175
Russian Federation, Moscow

Tatiana V. Konchugova

National Medical Research Center for Rehabilitation and Balneology

Email: yurovaov@nmicrk.ru
ORCID iD: 0000-0003-0991-8988
SPIN-code: 3198-9797

Dr. Sci. (Med.), Professor

Russian Federation, Moscow

References

  1. Whitcher JP, Srinivasan M, Upadhyay MP. Corneal blindness: a global perspective. Bull World Health Organ. 2001;79(3):214–221.
  2. Bhadange Y, Sharma S, Das S, Sahu SK. Role of liquid culture media in the laboratory diagnosis of microbial keratitis. Am J Ophthalmol. 2013;156(4):745–751. doi: 10.1016/j.ajo.2013.05.035
  3. Byrd LB, Martin N. Corneal ulcer. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021.
  4. Lu X, Ng DS, Zheng K, et al. Risk factors for endophthalmitis requiring evisceration or enucleation. Sci Rep. 2016;6:28100. doi: 10.1038/srep28100
  5. Hongyok T, Leelaprute W. Corneal ulcer leading to evisceration or enucleation in a tertiary eye care center in Thailand: clinical and microbiological characteristics. J Med Assoc Thail Chotmaihet Thangphaet. 2016;99(Suppl 2):S116–122.
  6. Gohua TI, Egorov VV, Smolyakova GP, Borisova TV. Clinical justification for the use of magnetophoresis of the drug longidase — a combined enzyme in the complex treatment of bacterial keratitis. Modern Technologies in Ophthalmology. 2018;(2):183–185. (In Russ).
  7. Egorov VV, Smolyakova GP, Gohua TI, Borisova TV. Clinical evaluation of a new physiotherapy technology in the complex treatment of bacterial inflammation of the cornea. Practical Medicine. 2017;2(9):72–77. (In Russ).
  8. Filatov VV. Infrasonic phonophoresis ― a new direction in the treatment of ophthalmopathology. Russian Pediatric Ophthalmology. 2013;(1):52–60. (In Russ).
  9. Frolov MA, Kazakova KA, Gonchar PA, Frolov AM. Sanitation of corneal ulcer by near-infrared laser radiation. Tochka Zreniya Vostok-Zapad. 2016;(2):135–137. (In Russ).
  10. Frolov MA. The use of a 1.44 micron diode laser coagulator for the treatment of corneal ulcers. In: VI Russian National Ophthalmological Forum: collection of scientific papers. Vol. 2. 2014. Р. 491–495. (In Russ).

Copyright (c) 2021 Eco-Vector



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies