Regression of spinal demyelination in a patient with leber's disease during long-term therapy with acupuncture and transcutaneous electroneurostimulation

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

In this paper, we demonstrate the effectiveness of the complex use of acupuncture and direct transcutaneous electroneurostimulation of the median, ulnar, tibial and peroneal nerves in treatment of patient with a demyelization changes in the spinal cord. At the same time, it was possible not only to reduce the severity of motor and sensory deficits, but also of Limb Spasticity, and also to cause a complete regression of demyelization changes in MRI.

Full Text

Restricted Access

About the authors

Mustafa Kh. Al-Zamil

Peoples' Friendship University of Russia; LLC "Olivia" Brain and Spine Clinic

Author for correspondence.
Email: alzamil@mail.ru
ORCID iD: 0000-0002-3643-982X
SPIN-code: 5487-9802

Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

Natalya G. Kulikova

Peoples' Friendship University of Russia

Email: alzamil@mail.ru
SPIN-code: 6895-0681

Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Ekaterina S. Vasilieva

Peoples' Friendship University of Russia

Email: alzamil@mail.ru
ORCID iD: 0000-0003-3087-3067
SPIN-code: 5423-8408

Dr. Sci. (Med.), Professor

Russian Federation, Moscow

References

  1. Tobore TO. Towards a comprehensive etiopathogenetic and pathophysiological theory of multiple sclerosis. Int J Neurosci. 2020;130(3):279–300. doi: 10.1080/00207454.2019
  2. Roussarie JP, Ruffie C, Brahic M. The role of myelin in Theiler’s virus persistence in the central nervous system. PLoS Pathog. 2007;3(2):e23. doi: 10.1371/journal.ppat.0030023
  3. Theiler M. Spontaneous encephalomyelitis of mice — a new virus disease. Science. 1934;80(2066):122.doi: 10.1126/science.80.2066.122-a
  4. Tsunoda I, Tanaka T, Terry EJ, Fujinami RS. Contrasting roles for axonal degeneration in an autoimmune versus viral model of multiple sclerosis: when can axonal injury be beneficial? Am J Pathol. 2007;170(1):214–226. doi: 10.2353/ajpath.2007.060683
  5. Pedley TA, Baxil CW, Morrell MJ. Epilepsy. In: Rowland LP, ed. Merritt’s Neurology. 10th. Philadelphia: Lippincott Williams & Wilkins; 2000. Р. 813–833.
  6. Stewart KA, Wilcox KS, Fujinami RS, White HS. Development of postinfection epilepsy after Theiler’s virus infection of C57BL/6 mice. J Neuropathol Exp Neurol. 2010;69(12):1210–1219.doi: 10.1097/NEN.0b013e3181ffc420
  7. Tsunoda I, Sato F, Omura S, et al. Three immune-mediated disease models induced by Theiler's virus: Multiple sclerosis, seizures and myocarditis. Clin Exp Neuroimmunol. 2016;7(4):330–345.doi: 10.1111/cen3.12341
  8. Fernández-Tenorio E. Transcutaneous electrical nerve stimulation for spasticity: A systematic review. Neurologia. 2019;34(7):451–460. doi: 10.1016/j.nrl.2016.06.009
  9. Garcia MA, Vargas CD. Is somatosensory electrical stimulation effective in relieving spasticity? A systematic review. Musculoskelet Neuronal Interact. 2019;19(3):317–325.
  10. Mills PB, Dossa F. Transcutaneous electrical nerve stimulation for management of limb spasticity: a systematic review. Am J Phys Med Rehabil. 2016;95(4):309–318.doi: 10.1097/PHM.0000000000000437
  11. Rozhkova VP, Al Zamil M, Kulikova NG. The combination of demyelinating lesions of the spinal cord, brain atrophy, progressive demyelinating polyneuropathy in a patient with Leber’sdisease. Clinical Neurology. 2019;(1):3–7.
  12. Al Zamil MK. To the question about the impact of tes therapy to vash indicators of pain in patients with polyneuropathy. International Journal of Medicine and Psychology. 2019;2(4):73–76.
  13. Al Zamil M, Kulikova N, Bezrukova O, et al. Effectiveness of transcutaneous electrical neurostimulation for treatment of diabetic distal polyneuropathy. Eur J Neurology. 2019;26(Suppl. 1):729.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download
2. Fig. 1. MRI of the cervical spine of patient A .: a - before treatment (the area of amplification of the MR signal at T2 is determined, starting at the C1 level and going down); b - after treatment (there are no signs of demyelination).

Download (146KB)
Indexing metadata
3. Fig. 2. MRI of the brain of patient A .: a - before treatment (there are signs of atrophy with a pronounced predominance of a subcortical character; non-coarse anterior and lateral leukoaraiosis); b - after treatment (there are signs of moderate brain atrophy with a pronounced predominance of subcortical character; non-coarse anterior and lateral leukoaraiosis. Compared with the previous record, there is a positive trend in reducing the severity of lateral leukoaraiosis).

Download (124KB)
Indexing metadata

Copyright (c) 2021 Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86508 от 11.12.2023. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80650 от 15.03.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies