USE OF HYPERTHERMIA IN TREATMENT OF PATIENTS WITH NON-ONCOLOGICAL DISEASES

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Abstract

An electronic search for publications on the results of the use of hyperthermia (HT) in medicine was carried out using the Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RSCI, international and regional journals, materials of international congresses, congresses and conferences. The review analyzes the results of experimental and clinical studies on local hyperthermia (LHT) in inflammatory, allergic and other diseases. In vitro experiments have shown that LHT increases the antibacterial activity of serum, as well as the expression of anti-inflammatory cytokines. Clinical studies have established a positive therapeutic effect of LHT in rhinitis of various etiologies, purulent sinusitis, viral human papilloma, fibromyalgia, injuries of the musculoskeletal system, chronic prostatitis. Analysis shows that the therapeutic effect of LHT is associated not only with direct bacteriostatic and bactericidal actions, but also with an indirect effect on the course of the disease, namely, modulation of the activity of antigen-presenting cells, increased blood and lymph circulation, and increased metabolism. It is also important that LHT increases the effectiveness of antibiotic therapy in drug-resistant forms of the inflammatory process. The wide range of beneficial biological effects of LHT on the body as a whole and on pathological processes makes it possible to consider it as a promising therapeutic method in various fields of medicine.

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orazakhmet Kurpeshev

ANO Siberian Scientific Research Institute of Hyperthermia

Author for correspondence.
Email: kurpeshev-ok@yandex.ru
ORCID iD: 0000-0003-3219-1596

PhD, MD, freelance consultant

Russian Federation, 633205, Novosibirsk region, Iskitim-5, Russia.

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