One-pot synthesis of 3-carbomoyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid

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Abstract

A one-pot method for the synthesis of 3-carbomoyl-2-oxo-1,2-dihydropyridine-4-carboxylic acids has been developed, which consists in the interaction of 4-oxoalkane-1,1,2,2-tetracarbonitriles with water and the hydrolysis of the resulting mixture of 2-oxo-1, 2-dihydropyridine-3,4-dicarbonitrile and 2-oxo-4-cyano-1,2-dihydropyridine-3-carboxamide with sodium hydroxide solution.

About the authors

S. V Fedoseev

I.N. Ul'yanov Chuvash State University

Email: sergey.fedoseev88@gmail.com

K. V Lipin

I.N. Ul'yanov Chuvash State University

Email: sergey.fedoseev88@gmail.com

O. V Ershov

I.N. Ul'yanov Chuvash State University

Email: sergey.fedoseev88@gmail.com

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