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Photodynamic therapy for correction of involutive facial skin changes
- Authors: Surkichin S.I.1, Bochkova N.V.1, Kholupova L.S.1
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Affiliations:
- Central State Medical Academy of the Administrative Department of the President of Russia
- Issue: Vol 19, No 3 (2020)
- Pages: 140-144
- Section: Original studies
- URL: https://rjpbr.com/1681-3456/article/view/57958
- DOI: https://doi.org/10.17816/1681-3456-2020-19-3-1
- ID: 57958
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Abstract
Background. The appearance of the skin is of high social importance, largely determining the behavior and self-confidence of a person. The relevance of methods for the correction of involutive skin changes is growing every year. One modern treatment for photodamaged skin is photodynamic therapy.
Objective: the study evaluated the effectiveness of photodynamic therapy using chlorin E6 as a photosensitizer for the correction of involutive changes in the skin of the face compared to using only light exposure.
Methods. The study involved patients aged 40−60 years with signs of involutive changes in the skin of the face. In group 1 (n = 36), patients underwent therapy using only light coherent radiation. In group 2 (n = 35), patients underwent PDT using light coherent radiation.
Results. According to the results of elastometry, corneometry, assessment of transepidermal water loss, ultrasound examination of the skin in group 2, more positive indicators were obtained than in group 1. When assessing safety, the results in groups 1 and 2 are comparable.
Conclusions. The method of photodynamic therapy using chlorin E6 can be recommended for course use in wide clinical practice.
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About the authors
S. I. Surkichin
Central State Medical Academy of the Administrative Department of the President of Russia
Email: info@eco-vector.com
ORCID iD: 0000-0003-0521-0333
PhD
Russian FederationN. V. Bochkova
Central State Medical Academy of the Administrative Department of the President of Russia
Email: info@eco-vector.com
ORCID iD: 0000-0001-6457-7130
Russian Federation
L. S. Kholupova
Central State Medical Academy of the Administrative Department of the President of Russia
Author for correspondence.
Email: karsekals@gmail.com
ORCID iD: 0000-0002-2781-4587
Russian Federation
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