Optimization of short-term courses of intensive combined therapy with the use of physical factors and regulators of energy metabolism for the treatment of patients presenting with ostoarthrosis

The authors report the development of a method for the enhancement of the efficacy of short-term courses of intensive combined treatment of patients presenting with ostoarthrosis by including intake of a succinic acid-containing preparation as a regulator of energy metabolism. It was shown that intensive (on a day-to-day basis) combined physio-, balneo-, and peloidotherapy along with regular intake of the succinate-based drug permitted to decrease the frequency of clinical manifestations of balneoresponsiveness, optimize the functional capacity of the main regulatory systems and energy production. These changes were associated with the increase of non-specific resistance of the organism and contributed to the reduction of severity or complete elimination of clinical symptoms of the disease within 14-16 days or much sooner than under effect of traditional therapy.

intensive combined therapy with the use of physical factors, osteoarthrosis, regulators of energy metabolism, succinic acid