The potential of hemolasertherapy for the correction of clinical and functional disturbances in psoriatic patients

The present study was designed to compare the efficacy of the treatment of 104 patients with psoriasis allocated to three groups, one managed by PUVA therapy, another by intravenous laser irradiation of the blood, and the third by the combination of these two methods. Analysis of the data obtained has demonstrated that inflammatory symptoms of psoriasis rapidly regressed under the influence of laser irradiation while the combination of the two methods further accelerated the regression of infiltrative manifestations. Intravenous laserotherapy stimulated activity of the main antioxidant enzymes in erythrocytes that play an important role in the antioxidative protection of these cells. In contrast, PUVA therapy alone did not cause changes in the antioxidant status of the patients. Thermography revealed lowering of the temperature at the affected skin areas under effect of the treatment in all three groups of the patients, but this effect was reached quicker and was more pronounced after 3-4 seances of laserotherapy than after PUVA therapy. The results of the study indicate that the introduction of intravenous laser irradiation of the blood into the combined treatment of psoriasis not only accelerates regression of the main clinical manifestations of the disease but also exerts beneficial action on microcirculation and disbalance of pro- and antioxidant systems.

psoriasis, laser irradiation, PUVA therapy, antioxidant system, thermography, microcirculation