The influence of combined phototherapy on the serum defensin level in patients presenting with lichen planus ruber


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Abstract

The serum alpha-defensin (HNP1-3) level in neutrophils obtained from patients presenting with lichen planus ruber was shown to undergo appreciable changes suggesting their involvement in pathogensis of this condition. The combined treatment using narrow-band middle and long wavelength radiation was shown to markedly reduce objective and subjective manifestations of lichen planus ruber and promote normalization of serum alpha-defensin levels.

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