A Comprehensive Review on Trigonella foenum-graecum L. with Special Reference to Unani Medicine

  • Authors: Khatoon F.1, Azahar M.2, Uddin Q.3, Husain N.4, Moin M.5, Khan S.6
  • Affiliations:
    1. Department of Moalajat (Unani Medicine), National Research Institute of Unani Medicine, for Skin Disorders (NRIUMSD
    2. Department of Medicine (Unani), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)
    3. Department of Moalajat (Unani Medicine), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)
    4. Department of Medicine (Unani), Luqman Unani Medical College Hospital and Research Center
    5. Department of Pharmacology (Unani), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)
    6. Department of Pharmacology (Unani, National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)
  • Issue: Vol 27, No 2 (2024)
  • Pages: 187-202
  • Section: Chemistry
  • URL: https://rjpbr.com/1386-2073/article/view/644594
  • DOI: https://doi.org/10.2174/1386207326666230504112848
  • ID: 644594

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Abstract

Trigonella foenum-graecum L., commonly known as Ḥulba or Methi in Unani medicine, is an annual self-pollinating plant belonging to the Leguminosae family. It has been utilized for centuries to treat a wide range of diseases, and modern research has supported its traditional medicinal claims. In this study, the authors have conducted manual and online searches to gather and summarize the scientific literature on Ḥulba. This article seeks to underscore the potential of Ḥulba in addressing a variety of health conditions as identified by esteemed classical Unani scholars, as well as to investigate its phytochemistry and pharmacological properties in contemporary medicine. The authors have utilized electronic databases, such as PubMed, Science Direct, DOAJ, Google Scholar, and Ayush Research Portal to filter published material. According to the gathered literature, Unani physicians have consistently recommended Ḥulba seeds for a variety of ailments, such as indigestion, flatulence, colitis, arthritis, backache, paralysis, headaches, common cold, cough, bronchial asthma, diabetes mellitus, vitiligo, and pityriasis. Additionally, the seeds and green leaves of Ḥulba contain several chemical constituents, such as alkaloids, flavonoids, steroids, saponins, and amino acids. Furthermore, several pharmacological studies have demonstrated that Ḥulba possesses various properties, including antidiabetic, antispasmodic, hypolipidemic, immunological, antibacterial, anthelmintic, antiinflammatory, analgesic, and antioxidant activities. Based on the available evidence, it can be concluded that Ḥulba has been effectively used in Unani medicine for treating a wide range of diseases. Unani scholars have extensively documented its pharmacological properties, which have been supported by modern research studies. However, further research is necessary to validate some of the claims made in traditional medicine using scientific parameters.

About the authors

Faiza Khatoon

Department of Moalajat (Unani Medicine), National Research Institute of Unani Medicine, for Skin Disorders (NRIUMSD

Email: info@benthamscience.net

Mohd Azahar

Department of Medicine (Unani), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)

Email: info@benthamscience.net

Qamar Uddin

Department of Moalajat (Unani Medicine), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)

Email: info@benthamscience.net

Nazim Husain

Department of Medicine (Unani), Luqman Unani Medical College Hospital and Research Center

Author for correspondence.
Email: info@benthamscience.net

Md Moin

Department of Pharmacology (Unani), National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)

Email: info@benthamscience.net

Shayni Khan

Department of Pharmacology (Unani, National Research Institute of Unani Medicine for Skin Disorders (NRIUMSD)

Email: info@benthamscience.net

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