Oxocarbon Acids and their Derivatives in Biological and Medicinal Chemistry
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Oxocarbon Acids and their Derivatives in Biological and Medicinal Chemistry |
| 2. | Creator | Author's name, affiliation, country | Amanda Ratto; Department of Chemistry, University of Waterloo |
| 2. | Creator | Author's name, affiliation, country | John Honek; Department of Chemistry, University of Waterloo |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | Deltic acid; squaric; croconic; rhodizonic; oxocarbon acids; bioisosteres. |
| 4. | Description | Abstract | The biological and medicinal chemistry of the oxocarbon acids 2,3-dihydroxycycloprop-2-en-1-one (deltic acid), 3,4-dihydroxycyclobut-3-ene-1,2-dione (squaric acid), 4,5-dihydroxy-4-cyclopentene-1,2,3-trione (croconic acid), 5,6-dihydroxycyclohex-5-ene-1,2,3,4-tetrone (rhodizonic acid) and their derivatives is reviewed and their key chemical properties and reactions are discussed. Applications of these compounds as potential bioisosteres in biological and medicinal chemistry are examined. Reviewed areas include cell imaging, bioconjugation reactions, antiviral, antibacterial, anticancer, enzyme inhibition, and receptor pharmacology. |
| 5. | Publisher | Organizing agency, location | Bentham Science |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (DD-MM-YYYY) | 01.01.2024 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | Research Article |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://rjpbr.com/0929-8673/article/view/644137 |
| 10. | Identifier | Digital Object Identifier (DOI) | 10.2174/0929867330666230313141452 |
| 11. | Source | Title; vol., no. (year) | Current Medicinal Chemistry; Vol 31, No 10 (2024) |
| 12. | Language | English=en | |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
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