Multiple Natural Polymers in Drug and Gene Delivery Systems


Дәйексөз келтіру

Толық мәтін

Аннотация

Background:Natural polymers are organic compounds produced by living organisms. In nature, they exist in three main forms, including proteins, polysaccharides, and nucleic acids. In recent years, with the continuous research on drug and gene delivery systems, scholars have found that natural polymers have promising applications in drug and gene delivery systems due to their excellent properties such as biocompatibility, biodegradability, low immunogenicity, and easy modification. However, since the structure, physicochemical properties, pharmacological properties and biological characteristics of biopolymer molecules have not yet been entirely understood, further studies are required before large-scale clinical application. This review focuses on recent advances in the representative natural polymers such as proteins (albumin, collagen, elastin), polysaccharides (chitosan, alginate, cellulose) and nucleic acids. We introduce the characteristics of various types of natural polymers, and further outline the characterization methods and delivery forms of these natural polymers. Finally, we discuss possible challenges for natural polymers in subsequent experimental studies and clinical applications. It provides an important strategy for the clinical application of natural polymers in drug and gene delivery systems.

Авторлар туралы

Zhengfa Jiang

Department of Orthopedics, First Affiliated Hospital of Zhengzhou University

Email: info@benthamscience.net

Zongmian Song

Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University

Email: info@benthamscience.net

Chen Cao

Department of Orthopedics, Zhengzhou University People’s Hospital

Email: info@benthamscience.net

Miaoheng Yan

Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University

Email: info@benthamscience.net

Zhendong Liu

Department of Orthopedics, Zhengzhou University People’s Hospital

Email: info@benthamscience.net

Xingbo Cheng

Department of Orthopedics, Zhengzhou University People’s Hospital

Email: info@benthamscience.net

Hongbo Wang

Department of Orthopedics, Zhengzhou University People’s Hospital

Email: info@benthamscience.net

Qingnan Wang

Department of Orthopedics, Zhengzhou University People’s Hospital

Email: info@benthamscience.net

Hongjian Liu

Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University

Хат алмасуға жауапты Автор.
Email: info@benthamscience.net

Songfeng Chen

Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University

Хат алмасуға жауапты Автор.
Email: info@benthamscience.net

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