电邮这篇文章 Scientific substantiation of the national list of chemicals affecting the endocrine system
- 作者: Khamidulina K.K.1,2, Tarasova E.V.1, Zamkova I.V.1, Dorofeeva E.V.1, Araslanov I.N.1, Aniskova Y.Y.1, Proskurina A.S.1,2, Rabikova D.N.1,2, Lastovetskiy M.L.1, Nazarenko A.K.1
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隶属关系:
- Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
- Russian Medical Academy of Continuous Professional Education, RF Ministry of Health
- 期: 编号 2 (2022)
- 页面: 108-114
- 栏目: Original Study
- ##submission.datePublished##: 21.04.2022
- URL: https://rjpbr.com/0869-7922/article/view/641423
- DOI: https://doi.org/10.47470/0869-7922-2022-30-2-108-114
- ID: 641423
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Introduction. Today in the world, along with mutagens, carcinogens, reprotoxicants, chemicals that affect the endocrine system are of serious concern. Therefore, the purpose of our research was the scientific substantiation of the national list of endocrine disruptors.
Materials and methods. In order to create a national list of substances that have an effect on the endocrine system, for the selection of candidate substances, an analysis of legislation and lists of potential endocrine disruptors of the European Union, the USA, Canada, and India was made. All substances were identified by CAS numbers, areas of application and classified according to the degree of danger to the endocrine system.
Results. The draft list of endocrine disruptors circulating in the Russian Federation includes 494 chemicals used in medicine, agriculture, chemical, food, perfume and cosmetic industries. There are 19 substances in class 1A (known endocrine disruptor), 193 substances in class 1B (probable endocrine disruptor), 250 substances in class 2 (suspected endocrine disruptors), and 32 substances in class 3 (endocrine disruptors).
Conclusion. On the territory of the Russian Federation in various areas of the economy, chemicals that destroy the endocrine system are widely used. Of particular concern is the use of endocrine disruptors of hazard class 1B in perfumery, cosmetics and food products.
作者简介
Khalidya Khamidulina
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health
编辑信件的主要联系方式.
Email: director@rosreg.info
ORCID iD: 0000-0001-7319-5337
Doctor of medical sciences; director of the Russian Register of Potentially Hazardous Chemical and Biological Substances — Branch of F.F. Erisman Federal Scientific Center of Hygiene, Rospotrebnadzor, 121087, Moscow, Russian Federation; Professor, Head of the Department of Hygiene, Russian Medical Academy of Continuous Professional Education, RF Ministry of Health, 125993, Moscow, Russian Federation.
e-mail: director@rosreg.info
俄罗斯联邦Elena Tarasova
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0002-4020-3123
Кандидат химических наук, химик-эксперт филиала РПОХБВ ФБУН ФНЦГ им. Ф.Ф. Эрисмана Роспотребнадзора, г. Москва.
e-mail: secretary@rosreg.info
俄罗斯联邦Irina Zamkova
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0002-7959-7246
Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.
e-mail: secretary@rosreg.info
俄罗斯联邦Ekaterina Dorofeeva
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0001-8901-7914
Начальник информационно-аналитического отдела филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.
e-mail: secretary@rosreg.info
俄罗斯联邦Ilgiz Araslanov
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0001-7694-0646
Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва
e-mail: secretary@rosreg.info
俄罗斯联邦Yuliya Aniskova
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0002-6384-0408
Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва
e-mail: secretary@rosreg.info
俄罗斯联邦Angelina Proskurina
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health
Email: proskurina-as@rosreg.info
ORCID iD: 0000-0003-2124-6440
Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, ассистент кафедры гигиены ФГБОУ ДПО РМАНПО Минздрава России, г. Москва.
e-mail: proskurina-as@rosreg.info
俄罗斯联邦Dinara Rabikova
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health
Email: rabikova_dn@rosreg.info
ORCID iD: 0000-0003-3965-7600
Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, ассистент кафедры гигиены ФГБОУ ДПО РМАНПО Минздрава России.
e-mail: rabikova_dn@rosreg.info
俄罗斯联邦Michail Lastovetskiy
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0001-9887-0626
Химик-эксперт филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.
e-mail: secretary@rosreg.info
俄罗斯联邦Andrey Nazarenko
Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor
Email: secretary@rosreg.info
ORCID iD: 0000-0003-0178-4540
Химик-эксперт филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.
e-mail: secretary@rosreg.info
俄罗斯联邦参考
- Khamidulina Kh.Кh., Tarasova E.V., Zamkova I.V., Dorofeeva E.V., Araslanov I.N., Aniskova Yu.Yu., Proskurina A.S., Rabikova D.N. International Approaches to Hazard Assessment and Classification of Endocrine Disruptors. Hygiena i Sanitariya. 2021;100 ( 12): 1372-6. (in Russian)
- Candidate List of Substances of Very High Concern for Authorisation).
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- Regulation (EC) № 1272/2008 Classification, packaging and labelling of chemical substances and mixtures (CLP).
- Database of Endocrine Disrupting Chemicals and their Toxicity profiles (DEDuCT), accessible at: https://cb.imsc.res.in/deduct/
- Karthikeyan B.S., Ravichandran J., Mohanraj K., Vivek-Ananth R.P., Samal A. A curated knowledgebase on endocrine disrupting chemicals and their biological systems-level perturbations. Science of the Total Environment. 2019; 692: 281-96.
- Karthikeyan B.S., Ravichandran J., Aparna S.R., Samal A. DEDuCT 2.0: An updated knowledgebase and an exploration of the current regulations and guidelines from the perspective of endocrine disrupting chemicals. Chemosphere. 2021; 267: 128898.
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- PubChem. www.pubchem.ncbi.nim.nih.gov
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