电邮这篇文章 EXPERIMENTAL EVALUATION OF THE ELECTROMAGNETIC RADIATION PROTECTIVE ACTION AGAINST HYDRAZINE TOXICITY EFFECT
- 作者: Kokaya A.A.1, Kozyakov V.P.2, Mukhina I.V.1
-
隶属关系:
- Medical University, Nizhny Novgorod State Medical Academy, Russian Ministry of Health, Central Research Laboratory
- Research Institute of Occupational Pathology and Human Ecology of the Federal Medical-Biological Agency of Russia
- 期: 编号 6 (2014)
- 页面: 28-35
- 栏目: Articles
- ##submission.datePublished##: 22.12.2014
- URL: https://rjpbr.com/0869-7922/article/view/641390
- DOI: https://doi.org/10.15690/vramn546
- ID: 641390
如何引用文章
全文:
详细
It was found out that the exposure of rats to asymmetric dimethylhydrazine in a dose of 100 mg/kg leads to acute functional disorders of the central nervous system, toxic lesion of a number of vitally important organs during the two first hours. During the first 4 hours of intoxication, the survival of rats in control groups was 10% to 60%, a day after it did not exceed 20% and in some cases 100% lethality was already observed in the first hours of intoxication. The preventive exposure to electromagnetic radiation modulated by the preparation with the tissue of the brain pituitary-hypothalamic part in newborn infant rat (P1-4) over 4 days with a total exposition of 270 min. increased the rat resistance to the toxic action of asymmetric dimethylhydrazine. In that case the survival of rats over the first 4 hours of intoxication was of 80-90% and a day after lowered up to 40-70%. The corrective action of the given type of radiation with a total exposure time of 150 min. also increased the rat resistance to toxic effect of asymmetric dimethylhydrazine in the indicated dose. In that case the survival in the first 4 hours of intoxication was 80%-90% and 50%-80%. during the first days of intoxication.
作者简介
Anna Kokaya
Medical University, Nizhny Novgorod State Medical Academy, Russian Ministry of Health, Central Research Laboratory
编辑信件的主要联系方式.
Email: noemail@neicon.ru
Кандидат медицинских наук, старший научный сотрудник отдела нейрофизиологии и экспериментального моделирования ГБОУ ВПО «Нижегородская государственная медицинская академия» Министерства здравоохранения России, ЦНИЛ, 603004, г. Нижний Новгород
e-mail: kann9988@gmail.com
俄罗斯联邦Vladimir Kozyakov
Research Institute of Occupational Pathology and Human Ecology of the Federal Medical-Biological Agency of Russia
Email: noemail@neicon.ru
Доктор медицинских наук, главный научный сотрудник научно-организационного отдела ФГУП «НИИ ГПЭЧ» ФМБА России, 188663, Ленинградская область, Всеволожский район, г.п. Кузьмоловский
e-mail: wpk@bk.ru
俄罗斯联邦Irina Mukhina
Medical University, Nizhny Novgorod State Medical Academy, Russian Ministry of Health, Central Research Laboratory
Email: noemail@neicon.ru
Доктор биологических наук, профессор, заведующий кафедрой нормальной физиологии ГОУ ВПО «Нижегородская государственная медицинская академия» Министерства здравоохранения России, ЦНИЛ, 603004, г. Нижний Новгород,
e-mail: mukchinaiv@mail.ru
俄罗斯联邦参考
- Biochemistry hydrazines / ed. NI Poryanoy. - Angarsk. - 2005. - 81 p.
- Buchachenko A.L. Radiation and other magnetic effects in chemical reactions / A.L Buchachenko. - M.: Knowledge, 2007. - 197 p.
- Buchachenko A.L. New isotopes in chemistry and biology / A.L Buchachenko. - Moscow: Nauka, 2007. - 185 p.
- Kokaya N.G. Effect of corrective and preventive effects of electromagnetic radiation modulated biological structure on the course of acute insulin deficiency in rats / N.G Kokaya, A.A. Kokaya, I.V. Mukhina // Modern Technologies in Medicine. - 2011. - № 3. - P. 11-15.
- Kokaya N.G. Morphological changes in the pancreas of rats with acute insulin deficiency correction electromagnetic radiation modulated biostructures / N.G Kok aya, A.A Kokaya, I.V. Mukhina / / Natural and Technical Sciences. - 2011.- № 3 (53 ). - P. 156-164 .
- Kokaya A.A. Specificity of action of electromagnetic radiation converted various biostructures / A.A. Kokaya [etc.] // Bulletin of the Russian Military Medical Academy. - 2012. - № ( 40). - 163-168.
- Kokaya A.A. Effects of electromagnetic radiation on the viability of hepatocytes in the toxic action of hydrazine / A.A. Kokaya [etc.] // Bulletin of the Russian Military Medical Academy. - 2013. - № ( 41). - P. 136-142.
- Kokaya , Sensitivity of neurons to low-intensity electromagnetic radiation of the toxic effect of hydrazine / A.A Kokaya , [etc.] / / Bulletin of the Russian Military Medical Academy. - 2013. - № ( 42). - P. 109-115 .
- Kokaya A.A. Long-term adaptive structural changes of the liver cells and rat pancreas in the correction of acute insulin deficiency electromagnetic radiation modulated biostructures / A.A. Kokaya, N.G. Kokaya, I.V. Mukhina // Med. Almanac. - 2011. - № 5. - P. 175-179.
- Mazur A.I. Electrochemical indicators / A.I. Mazur, V.N. Grachev. - M.: Radio and communication, 1985. - 178 p.
补充文件
