Email this article TOXICITY UNDER A SINGLE INTRAGASTRIC ADMINISTRATION OF THE ACTIVE CLATHRATE COMPLEX OF β-CYCLODEXTRIN WITH 3-(2-PHENYLETHYL)-2-THIOXO-1,3- THIAZOLIDIN-4-ONE
- Authors: Erimbetov K.T.1,2, Zemlyanoy R.A.1, Bondarenko E.K.2, Goncharova A.Y.2
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Affiliations:
- All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst
- Research Center «Park of Active Molecules»
- Issue: No 6 (2020)
- Pages: 59-62
- Section: New information on toxicity and hazard of chemical and biological substances
- Published: 04.01.2021
- URL: https://rjpbr.com/0869-7922/article/view/641270
- DOI: https://doi.org/10.36946/0869-7922-2020-6-59-62
- ID: 641270
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Abstract
The clathrate complex of 3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one with β-cyclodextrin in the form of a nanopowder with an average particle size of 40.5 nm, with a wide range of pharmacological properties, was developed for the first time. It belongs to class VI of relatively harmless drugs according to Hodge and to class 5 in accordance with GOST 32644-2014.
About the authors
K. T. Erimbetov
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst; Research Center «Park of Active Molecules»
Author for correspondence.
Email: erimbetovkt@mail.ru
Erimbetov Kenes Tagaevich
249013, Kaluga Region
Russian FederationR. A. Zemlyanoy
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst
Email: fake@neicon.ru
Zemlyanoy Ruslan Alexandrovich
249013, Kaluga Region
Russian FederationE. K. Bondarenko
Research Center «Park of Active Molecules»
Email: bondarenko@pam-alliance.ru
Bondarenko Ekaterina Valer’evna
Obninsk, Kaluga region
Russian FederationA. Ya. Goncharova
Research Center «Park of Active Molecules»
Email: goncharova@pam-alliance.ru
Goncharova Anna Yakovlevna
Obninsk, Kaluga region
Russian FederationReferences
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