Age features of the excretion of carbonilic compounds with urine in children in unexposed territory

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Introduction. Carbonyl compounds (CC) are pollutants affecting the population and occupying an exceptional position in various fields of human activity. A significant source of CC is tobacco smoke.

Material and methods. Urine samples of 278 children were analyzed by the method of gas chromatography. Additionally, there were studied dependencies of the content of the CC on the harmful chemical effects in living conditions: active and passive smoking. The assessment of the effect of smoking on formaldehyde emissions (FD) was carried out using the chi-square test for a 3x3 table.

Results. The results obtained on the content of CC in the urine in several age groups. FD concentrations, in general, were shown to be in the range from 1.2 to 207.1 μg/dm3. The highest values were observed in the children’s population of the age group up to 7 years and in the group of 15-17 years. For representatives of the 1st (up to 7 years) and 3rd (15–17 years) age groups, the concentrations of acetaldehyde and acetone were in the range: for acetaldehyde - from 4.0 to 179.7 µg/dm3, acetone - from 0.35 to 11.95 µg/dm3. A statistically significant direct relationship was found between active smoking and FD content in urine (rsp = 0.24, p = 0.033); the reverse is with acetone content (rsp = 0.23, p = 0.042), and the inverse correlation between acetaldehyde content and passive smoking (rsp = 0.23, p = 0.038).

Conclusion. The highest content of formaldehyde in the urine was found in groups “up to 7 years old” and “15–17 years old”. No age and gender differences in acetaldehyde and acetone concentrations were found.

作者简介

Olga Zhurba

East-Siberian Institute of Medical and Ecological Research

编辑信件的主要联系方式.
Email: zhurba99@gmail.com
ORCID iD: 0000-0002-9961-6408

MD, Ph.D., head of the laboratory of analytical ecotoxicology and biomonitoring of the East-Siberian Institution of Medical and Ecological Research, Angarsk, 665827, Russian Federation.

e-mail: zhurba99@gmail.com

俄罗斯联邦

N. Efimova

East-Siberian Institute of Medical and Ecological Research

Email: noemail@neicon.ru
ORCID iD: 0000-0001-7218-2147
俄罗斯联邦

A. Alekseenko

East-Siberian Institute of Medical and Ecological Research

Email: noemail@neicon.ru
ORCID iD: 0000-0003-4980-5304
俄罗斯联邦

A. Merinov

East-Siberian Institute of Medical and Ecological Research

Email: noemail@neicon.ru
ORCID iD: 0000-0001-7848-6432
俄罗斯联邦

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