Substantiation of the use of indices of the heart rate variability in predicting the development of polyneuropathies in workers of coal enterprises
- 作者: Gidayatova M.O.1, Martynov I.D.1, Yamshchikova A.V.1, Fleishman A.N.1
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隶属关系:
- Research Institute for Complex Problems of Hygiene and Occupational Diseases
- 期: 卷 99, 编号 7 (2020)
- 页面: 688-692
- 栏目: OCCUPATIONAL HEALTH
- ##submission.datePublished##: 08.09.2020
- URL: https://rjpbr.com/0016-9900/article/view/639702
- DOI: https://doi.org/10.47470/0016-9900-2020-99-7-688-692
- ID: 639702
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Introduction. One of the most common forms of occupational diseases of the peripheral nervous system is autonomic-sensory polyneuropathy. For Kuzbass, which is one of the leaders in coal mining, the problem of early diagnosis and prevention of polyneuropathies is the most urgent.
The purpose of this study was to determine autonomic disorders and their role in the development of occupational polyneuropathy in workers of coal enterprises in Kuzbass.
Material and methods. 72 male miners aged from 40 to 64 years with working experience from 15 to 36 years were examined. The control group consisted of 18 subjects of the same age, engaged in light physical or mental work that had no occupational risk factors. To assess the degree of peripheral nerve damage electroneuromyography was performed in all cases; indices of spectral and nonlinear heart rate variability were used to determine the state of autonomic regulation.
Results. No signs of polyneuropathy were detected in 20 subjects of the examined workers of coal enterprises according to electroneuromyography data. The miners with diagnosed polyneuropathy were divided into 3 groups according to the severity of the lesion of the impulse conduction along the peripheral nerves. In the miners with no signs of polyneuropathy, who exposed to harmful production factors, a statistically significant decrease in the power of high-frequency oscillations of the heart rate variability spectrum was determined. The subjects with initial disorders of the impulse conduction showed a progressive decrease in high-frequency oscillations, with moderate signs of polyneuropathy, there were a sympathetic predominance and increased influence of suprasegmental autonomic centers. In the development of severe disorders of the impulse conduction along the peripheral nerves, depression of oscillations in all frequency ranges and rigidity of the heart rate are characteristic.
Conclusion. The obtained data confirm the influence of autonomic dysfunction on the development of occupational polyneuropathy. The analysis of heart rate variability is an important tool for evaluating autonomic regulation and can be used in mass medical examinations. A decrease in spectral and nonlinear parameters in coal-mining workers is an early sign of the disorder of autonomic regulation, which allows predicting the occurrence and development of peripheral nerve damage.
作者简介
Margarita Gidayatova
Research Institute for Complex Problems of Hygiene and Occupational Diseases
编辑信件的主要联系方式.
Email: samodurova.margarita@mail.ru
ORCID iD: 0000-0002-8003-036X
MD, researcher of the laboratory for applied neurophysiology, neurologist, Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation. 俄罗斯联邦
Ilya Martynov
Research Institute for Complex Problems of Hygiene and Occupational Diseases
Email: noemail@neicon.ru
ORCID iD: 0000-0001-5098-9185
俄罗斯联邦
Anastasia Yamshchikova
Research Institute for Complex Problems of Hygiene and Occupational Diseases
Email: noemail@neicon.ru
ORCID iD: 0000-0002-6609-8923
俄罗斯联邦
Arnold Fleishman
Research Institute for Complex Problems of Hygiene and Occupational Diseases
Email: noemail@neicon.ru
ORCID iD: 0000-0002-2823-4074
俄罗斯联邦
参考
- Kapuścińska K., Urbanik A. High-frequency ultrasound in carpal tunnel syndrome: assessment of patient eligibility for surgical treatment. J Ultrason. 2015; 15(62): 283–91. https://doi.org/10.15557/JoU.2015.0025
- Artamonova V.G., Mukhin N.A. Occupational Diseases: A Textbook [Professional’nye bolezni: Uchebnik]. Moscow: Meditsina; 2004. (in Russian)
- Fleishman A.N. Slow oscillatory processes of hemodynamics: results and prospects of fundamental and applied research. Meditsina v Kuzbasse. 2004; 3(1): 61–3. (in Russian)
- Gemne G. Pathophysiology of white fingers in workers using hand-held vibration tools. Nagoya J Med Sci. 1994; 57(Suppl.): 87–97.
- Filimonov S.N., Panev N.I., Korotenko O.Yu., Evseeva N.A., Danilov I.P., Zatsepina O.V. Prevalence of somatic pathology in coal mine workers with occupational respiratory diseases. Meditsina truda i promyshlennaya ekologiya. 2019; 59(6): 381–4. https://doi.org/10.31089/1026-9428-2019-59-6-381-384 (in Russian)
- Mukhin N.A., Kosarev B.B., Babanov S.A., Fomin V.V. Occupational Diseases [Professional’nye bolezni]. Moscow: GEOTAR-Media; 2016. (in Russian)
- Yan’shina E.N., Lyubchenko P.N., Yan’shin N.P., Kasatkina L.F., Samoylov M.I. Multiple local involvement of peripheral nerves in workers suffering from occupational hands disorders. Meditsina truda i promyshlennaya ekologiya. 2009; (2): 24–8. (in Russian)
- Yamshchikova A.V., Fleishman A.N., Gidayatova M.O., Kungurova A.A. Indicators of the relationship between heart rate variability and levels of glycemia and cholesterol in vibration pathology. Meditsina truda i promyshlennaya ekologiya. 2019; 59(6): 359–63. https://doi.org/10.31089/1026-9428-2019-59-6-359-363 (in Russian)
- Martynov I.D. Early diagnosis of the hemodynamic regulation disorders in orthostasis. Byulleten’ Vostochno-Sibirskogo nauchnogo tsentra Sibirskogo otdeleniya Rossiyskoy akademii meditsinskikh nauk. 2016; 1(5): 30-4. (in Russian)
- Fleishman A.N., Korablina T.V., Khaliulin I.G., Petrovskiy S.A., Neretin A.A. Sex differences of VLF100 and VLF50 spectrum of heart rate variability in healthy individuals of young age and older subjects with vascular pathology in terms of seven-test, hyperventilation and orthostasis. Meditsina v Kuzbasse. 2017; 16(4): 23–33. (in Russian)
- Fleishman A.N. Heart Rate Variability and Slow Hemodynamic Oscillations: Nonlinear Phenomena in Clinical Practice [Variabel’nost’ ritma serdtsa i medlennye kolebaniya gemodinamiki: nelineynye fenomeny v klinicheskoy praktike]. Novosibirsk; 2009. (in Russian)
- Yamshchikova A.V., Fleishman A.N., Gidayatova M.O. Сomorbid conditions in the vibration disease patients. Gigiena i sanitariya. 2019; 98(7): 718–22. https://doi.org/10.18821/0016-9900-2019-98-7-718-722 (in Russian)
- Kochetova O.A., Mal’kova N.Yu. Study of working conditions in patients with occupational polyneuropathy of upper extremities. Gigiena i sanitariya. 2017; 96(7): 636–41. https://doi.org/10.1882/0016-9900-2017-96-7-636-640 (in Russian)
- Gerus A.Yu., Fleishman A.N. Features of heart rate variability at sick with type 2 diabetes. Vestnik Novosibirskogo gosudarstvennogo universiteta. Seriya: Biologiya, klinicheskaya meditsina. 2010; 8(1): 96–100. (in Russian)
- Bokeriya L.A., Bokeriya O.L., Volkovskaya I.V. Heart rate variability: measurement methods, interpretation, clinical use. Annaly aritmologii. 2009; 6(4): 21–32. (in Russian)
- Chekeeva N.T., Shleyfer S.G., Bebinov E.M. Conditions of the heart rate variability in patients with cerebrovascular pathology in low-mountain area. Neyrokhirurgiya i nevrologiya Kazakhstana. 2018; (2): 51. (in Russian)
- Malik R.A., Veves A., Tesfaye S., Smith G., Cameron N., Zochodne D., et al. Small fibre neuropathy: role in the diagnosis of diabetic sensorimotor polyneuropathy. Diabetes Metab. Res. Rev. 2011; 27(7): 678–84. https://doi.org/10.1002/dmrr.1222
- Serra J., Collado A., Solà R., Antonelli F., Torres X., Salgueiro M. et al. Hyperexcitable C nociceptors in fibromyalgia. Ann. Neurol. 2014; 75(2): 196–208. https://doi.org/10.1002/ana.24065
- Van Acker N., Ragé M., Slyudts E., Knaapen M.W., De Bie M., Timmers M. et al. Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy? BMC Res Notes. 2016; 9: 280. https://doi.org/10.1186/s13104-016-2085-4
- Amanbekov U.A., Battakova Sh.B., Otarbaeva M.B., Fazylova D.A., Abdikulova A.A. State of autonomous nervous system in vibration disease in miners. Meditsina truda i promyshlennaya ekologiya. 2006; (4): 8–10. (in Russian)
- Aleynikova T.V. Heart rate variability (literature review). Problemy zdorov’ya i ekologii. 2012; (1): 17–23. (in Russian)
- Suponeva N.A., Belova N.V., Zaytseva N.I., Yusupova D.G., Lagoda D.Yu., Korepina O.S. et al. Small fiber neuropathy. Annaly klinicheskoy i eksperimental’noy nevrologii. 2017; 11(1): 73–9. (in Russian)
- Babanov S.A., Baraeva R.A. Polyneuropathy: differential diagnosis, features of pharmacotherapy. Vrach. 2014; (5): 13–9. (in Russian)
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