Assessing the Genetic Diversity of Five Cattle Breeds Using SNP Markers Associated with Health

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Currently genetic evaluation of animals is an important part of the development of the agricultural complex. The improvement of molecular technologies every year makes it possible to carry out genetic research aimed at finding the most valuable animals in a cheaper and faster way. Indigenous breeds of cattle are an attractive object for such research because they have greater adaptive potential and resistance to diseases. However, modern comparative data on the genetic diversity of most local breeds based on SNP markers associated with health are lacking. Genetic association tests using these genetic markers for the Tagil, Sychevskaya, Suksun and Istobenskaya breeds are still to be carried out. The purpose of this work was to compare the genetic diversity of five cattle breeds using SNP markers associated with the development of ketosis, mastitis and productive longevity.

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作者简介

M. Bytov

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

V. Zubareva

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

S. Volskaya

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

A. Isaeva

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

D. Nokhrin

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

Yu. Osipova

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

O. Sokolova

Ural Federal Agrarian Scientific Research Centre, Ural Branch of Russian Academy of Sciences

编辑信件的主要联系方式.
Email: nauka_sokolova@mail.ru
俄罗斯联邦, Ekaterinburg, 620142

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1. JATS XML
2. Fig. 1. Deviations of the observed genotype frequencies from those expected by HardyTo Weinberg for two studied breeds of dairy cattle according to rs109452259. The spread on the histogram indicates 95% CI based on the results of Monte Carlo simulation in the HW_TEST package.

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3. Fig. 2. Results of capillary electrophoresis of amplification products obtained using the developed TaqMan genotyping systems.

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4. Fig. 3. The ratio of the frequencies of the genotypes of the three polymorphisms in the Ural populations of dairy cattle on the de Finetti diagrams. The red parabola is the Hardy-Weinberg equilibrium ratio, the red labels are populations with a deviation from equilibrium.

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5. Fig. 4. The scheme of the model of genetic cleavage of the five studied cattle breeds according to the principle of the main coordinates.

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6. Fig. 5. The results of the evaluation of the nonequilibrium coupling of the studied polymorphisms for the Istobenskaya and Tagil cattle breeds.

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