Mutation rate estimates for Y chromosomal STRs in the Yakut population

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Abstract

The fine structure of the Y chromosome haplogroup N3a2-M1982 has been described, based on complete sequencing data of 23 men, indigenous residents of Yakutia, taking into account both SNP and STR mutations. The rate of mutation of STR markers of the Y chromosome in the Yakut population was calibrated using radiocarbon dating of a sample of a medieval man, Yana Young, found in the lower reaches of the Yana River in Yakutia. Our estimates of the mutation intensity constant of STR loci in 23 marker haplotypes of the N3a2-M1991 branch using 3 different calculation options (0.0032, 0.0024, 0.0032) turned out to be slightly lower than the global average value according to YHRD data (0.0033), and higher than the average over frequently used for STR loci a “genealogical” mutation rate (0.0021), but within the confidence interval do not contradict modern ideas about STR mutations rate of the Y chromosome.

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About the authors

D. S. Adamov

Ammosov North-Eastern Federal University

Author for correspondence.
Email: sardaanafedorova@mail.ru
Russian Federation, Yakutsk, 677013

S. A. Fedorova

Ammosov North-Eastern Federal University

Email: sardaanafedorova@mail.ru
Russian Federation, Yakutsk, 677013

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