The effectiveness of low-level laser therapy in the treatment of patients with post-COVID-19 erectile dysfunction

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BACKGROUND: Non-drug therapy has proven to be the most effective and convenient method in the treatment of patients with post-Covid erectile dysfunction. One of these treatments is low-level laser therapy. The advantage of this method is the high therapeutic effect of a low-intensity laser on the function of the pudendal nerve and on the endothelium of the vessels of the cavernous body.

AIM: To study the effectiveness of low-level laser therapy in the treatment of patients with post-Covid erectile dysfunction.

MATERIALS AND METHODS: Under our supervision from 2021 to 2023. At the medical center Medical Dental Institute there were 40 patients diagnosed with post-Covid erectile dysfunction. The control group (n=20) of patients underwent a 2-month course of standard drug therapy, and the main group, in addition to drug therapy, underwent a course of low-intensity laser therapy. Erectile function was assessed using the International Index of Erectile Function (IIEF) and quality of life was assessed using the Life Satisfaction Index (LSIA).

RESULTS: After treatment erectile function improved in the control group by 11.7% (p <0.05) and in the main group by 33.1% (p >0.05). The quality of life satisfaction in the control group increased by 28.7% (p <0.05) in the control group and by 87% (p <0.05) in the main group.

CONCLUSION: The use of a contact red laser with a wavelength of 635 nm was 1.8 times more effective than standard drug therapy in restoring erectile function. In addition, the improvement in life satisfaction during low-intensity laser therapy exceeded these indicators in the control group by 2 times.

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作者简介

Mustafa Al-Zamil

Peoples’ Friendship University of Russia; Brain and Spine Clinic "Olivia"; Medical Dental Institute

编辑信件的主要联系方式.
Email: alzamil@mail.ru
ORCID iD: 0000-0002-3643-982X
SPIN 代码: 3434-9150

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow; Podolsk; Moscow

Denis Zalozhnev

Medical Dental Institute

Email: olivia4967@mail.ru
ORCID iD: 0000-0001-8976-3378
俄罗斯联邦, Moscow

Ekaterina Vasilieva

Medical Dental Institute; Petrovsky National Research Centre of Surgery; Russian University of Medicine

Email: e_vasilieva@inbox.ru
ORCID iD: 0000-0003-3087-3067
SPIN 代码: 5423-8408

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow; Moscow; Moscow

Tigran Markosyan

Petrovsky National Research Centre of Surgery

Email: tigranich2006@yandex.ru
ORCID iD: 0000-0003-1464-5654
SPIN 代码: 5083-6824

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow

Nadezhda Kozyrkova

Ogarev Mordovia State University

Email: kozyrkova2000@gmail.com
俄罗斯联邦, Saransk

Ekaterina Maksimova

Ogarev Mordovia State University

Email: katyunya.maksimova.2000@mail.ru
俄罗斯联邦, Saransk

Marina Surkova

Ogarev Mordovia State University

Email: surkova120@mail.ru
ORCID iD: 0009-0005-6575-4035
俄罗斯联邦, Saransk

Natalya Korchazhkina

Petrovsky National Research Centre of Surgery

Email: n9857678103@gmail.com
ORCID iD: 0000-0001-6913-8778
SPIN 代码: 9733-7646

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow

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1. JATS XML
2. Fig. 1. Dynamics of erectile function, measured using the International Index of Erectile Function, against the background of treatment of patients with postcovical erectile dysfunction.

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3. Fig. 2. Dynamics of the quality of life satisfaction of patients with postovoid erectile dysfunction against the background of treatment.

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4. Fig. 3. Mechanism of red laser action on altered endothelium (explained in the text).

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5. Fig. 4. Positive response of altered vessels to low-intensity red band laser therapy.

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