Effects of a pulsed electromagnetic field on the course of osteoporosis in postmenopausal women

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

BACKGROUND: Pulsed electromagnetic field therapy is non-invasive, pain-relieving and preventing bone loss in osteoporosis. This study analyzes the effects of rehabilitation of postmenopausal women after spinal fracture after treatment with a pulsed electromagnetic field.

AIM: is to analyze the effect of pulsed electromagnetic field on fractures and osteoporosis after spinal fracture surgery.

MATERIAL AND METHODS: A randomized controlled trial was conducted, respectively, in the pulsed electromagnetic field treatment group (40 cases) and the control group (42 cases), respectively. The results of the assessment of health-related quality of life (HRQOL), back pain, body function, hip bone density at 1 month and 3 months after surgery were studied.

RESULTS: Compared with the control group, the pulsed electromagnetic field treatment group can significantly improve the psychological score, the 6-minute walk test, and the sitting position in a chair one month after surgery. And 3 months after surgery, the pulsed electromagnetic field treatment group can significantly improve health-related quality of life (HRQOL), back pain, and body function scores.

CONCLUSION: Pulsed electromagnetic field therapy has a positive effect on pain relief, functional changes in the body and bone loss after spinal fracture surgery.

Full Text

Restricted Access

About the authors

Yuri Yu. Byalovsky

Ryazan State Medical University

Author for correspondence.
Email: b_uu2610@mail.ru
ORCID iD: 0000-0002-6769-8277
SPIN-code: 6389-6643

MD, Dr. Sci. (Med.), Professor

Russian Federation, Ryazan

Aleksey V. Ivanov

Yelatma Instrument Making Enterprise

Email: ivanov@elamed.com
ORCID iD: 0000-0001-5961-892X
SPIN-code: 4597-8537
Russian Federation, Yelatma

Irina S. Rakitina

Ryazan State Medical University

Email: rakitina62@gmail.com
ORCID iD: 0000-0002-9406-1765
SPIN-code: 8427-9471

MD, Cand. Sci. (Med.), Associated Professor

Russian Federation, Ryazan

References

  1. Legrand MA, Chapurlat R. Imminent fracture risk. Joint Bone Spine. 2021;88(3):105105. doi: 10.1016/j.jbspin.2020.105105
  2. Balasubramanian A, Zhang J, Chen L, et al. Risk of subsequent fracture after prior fracture among older women. Osteoporos Int. 2019;30(1):79–92. doi: 10.1007/s00198-018-4732-1
  3. Hansen L, Petersen KD, Eriksen SA, et al. Subsequent fracture rates in a nationwide population-based cohort study with a 10-year perspective. Osteoporos Int. 2015;26(2):513–519. doi: 10.1007/s00198-014-2875-2
  4. Lems WF, Dreinhöfer KE, Bischoff-Ferrari H, et al. EULAR/EFORT recommendations for management of patients older than 50 years with a fragility fracture and prevention of subsequent fractures. Ann Rheumatic Dis. 2017;76(5):802–810. doi: 10.1136/annrheumdis-2016-210289
  5. Graafmans WC, Bouter LM, Lips P. The influence of physical activity and fractures on ultrasound parameters in elderly people. Osteoporos Int. 1998;8(5):449–454. doi: 10.1007/s001980050090
  6. Refai H, Radwan D, Hassanien N. Radiodensitometric assessment of the effect of pulsed electromagnetic field stimulation versus low intensity laser irradiation on mandibular fracture repair: a preliminary clinical trial. J Maxillofac Oral Surg. 2014;13(4):451–457. doi: 10.1007/s12663-013-0551-2
  7. Markov MS. Pulsed electromagnetic field therapy history, state of the art and future. Environmentalist. 2007;27(4):465–475.
  8. doi: 10.1007/s10669-007-9128-2
  9. Zhu S, He H, Zhang C, et al. Effects of pulsed electromagnetic fields on postmenopausal osteoporosis. Bioelectromagnetics. 2017;38(6):406–424. doi: 10.1002/bem.22065
  10. Mohajerani H, Tabeie F, Vossoughi F, et al. Effect of pulsed electromagnetic field on mandibular fracture healing: a randomized control trial (RCT). J Stomatol Oral Maxillofac Surg. 2019;120(5):390–396. doi: 10.1016/j.jormas.2019.02.022
  11. Carpenter LL, Janicak PG, Aaronson ST, et al. Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice. Depression Anxiety. 2012;29(7):587–596. doi: 10.1002/da.21969
  12. Buchbinder R, Osborne RH, Ebeling PR, et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med. 2009;361(6):557–568. doi: 10.1056/NEJMoa0900429
  13. Cummings SR, Ferrari S, Eastell R, et al. Vertebral fractures after discontinuation of denosumab: a post hoc analysis of the randomized placebo-controlled FREEDOM trial and its extension. J Bone Miner Res. 2018;33(2):190–198. doi: 10.1002/jbmr.3337
  14. Genant HK, Wu CY, van Kuijk C, Nevitt MC. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 1993;8(9):1137–1148. doi: 10.1002/jbmr.5650080915
  15. Dávila Castrodad M, Recai TM, Abraham MM, et al. Rehabilitation protocols following total knee arthroplasty: a review of study designs and outcome measures. Ann Transl Med. 2019; 7(Suppl 7): S255. doi: 10.21037/atm.2019.08.15
  16. Tang BM, Eslick GD, Nowson C, et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet. 2007;370(9588):657–666. doi: 10.1016/S0140-6736(07)61342-7
  17. Liu HF, Yang L, He HC, et al. Pulsed electromagnetic fields on postmenopausal osteoporosis in southwest China: a randomized, active-controlled clinical trial. Bioelectromagnetics. 2013;34(4):323–332. doi: 10.1002/bem.21770
  18. Badia X, Díez-Pérez A, Lahoz R, et al. The ECOS-16 questionnaire for the evaluation of health related quality of life in post-menopausal women with osteoporosis. Health Qual Life Outcomes. 2004;2(1):41. doi: 10.1186/1477-7525-2-41
  19. Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol group. Ann Med. 2001;33(5):337–343. doi: 10.3109/07853890109002087
  20. Scott J, Huskisson EC. Graphic representation of pain. Pain. 1976;2(2):175–184.
  21. Macko RF, Ivey FM, Forrester LW, et al. Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial. Stroke. 2005;36(10):2206–2211. doi: 10.1161/01.STR.0000181076.91805.89
  22. Jones CJ, Rikli RE, Max J, Noffal G. The reliability and validity of a chair sit-and-reach test as a measure of hamstring flexibility in older adults. Res Q Exerc Sport. 1998;69(4):338–343. doi: 10.1080/02701367.1998.10607708
  23. Suess O, Schomaker M, Cabraja M, et al. Empty polyetheretherketone (PEEK) cages in anterior cervical diskectomy and fusion (ACDF) show slow radiographic fusion that reduces clinical improvement: results from the prospective multicenter “PIERCE-PEEK” study. Patient Saf Surg. 2017;(11):12. doi: 10.1186/s13037-017-0128-y
  24. Kado DM, Huang MH, Nguyen CB, et al. Hyperkyphotic posture and risk of injurious falls in older persons: the Rancho Bernardo Study. J Gerontol A Biol Sci Med Sci. 2007;62(6):652–657. doi: 10.1093/gerona/62.6.652
  25. Adachi D, Loannidis G, Berger C, et al. The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int. 2001;12(11):903–908. doi: 10.1007/s001980170017
  26. Francis RM, Aspray TJ, Hide G, et al. Back pain in osteoporotic vertebral fractures. Osteoporos Int. 2008;19(7):895–903. doi: 10.1007/s00198-007-0530-x
  27. Bingefors K, Isacson D. Epidemiology, co-morbidity, and impact on health-related quality of life of self-reported headache and musculoskeletal pain–a gender perspective. Eur J Pain. 2004;8(5):435–450. doi: 10.1016/j.ejpain.2004.01.005
  28. Kanis JA, Johnell O, Oden A, et al. Long-term risk of osteoporotic fracture in Malmö. Osteoporos Int. 2000;11(8):669–674. doi: 10.1007/s001980070064
  29. Cooper C, Atkinson EJ, Jacobsen SJ, et al. Population-based study of survival after osteoporotic fractures. Am J Epidemiol. 1993;137(9):1001–1005. doi: 10.1093/oxfordjournals.aje.a116756
  30. Armingeat T, Brondino R, Pham T, et al. Intravenous pamidronate for pain relief in recent osteoporotic vertebral compression fracture: a randomized double-blind controlled study. Osteoporos Int. 2006;17(11):1659–1665. doi: 10.1007/s00198-006-0169-z
  31. Sinaki M. Exercise for patients with osteoporosis: management of vertebral compression fractures and trunk strengthening for fall prevention. PM R. 2012;(4):882–888. doi: 10.1016/j.pmrj.2012.10.008
  32. Stanghelle B, Bentzen H, Giangregorio L, et al. Effect of a resistance and balance exercise programme for women with osteoporosis and vertebral fracture: study protocol for a randomized controlled trial. BMC Musculoskeletal Disorders. 2018;19(1):100. doi: 10.1186/s12891-018-2021-y
  33. Marini S, Leoni E, Raggi A, et al. Proposal of an adapted physical activity exercise protocol for women with osteoporosis-related vertebral fractures: a pilot study to evaluate feasibility, safety, and effectiveness. Int J Environ Res Public Health. 2019;16(14):2562. doi: 10.3390/ijerph16142562
  34. Gerdhem P. Osteoporosis and fragility fractures: vertebral fractures. Best Pract Res Clin Rheumatol. 2013;27(6):743–755. doi: 10.1016/j.berh.2014.01.002
  35. Gan JC, Glazer PA. Electrical stimulation therapies for spinal fusions: current concepts. Eur Spine J. 2006;15(9):1301–1311. doi: 10.1007/s00586-006-0087-y
  36. Piazzolla A, Solarino G, Bizzoca D, et al. Capacitive coupling electric fields in the treatment of vertebral compression fractures. J Biol Regul Homeost Agents. 2015;29(3):637–646.
  37. Massari L, Brodano GB, Setti S, et al. Does capacitively coupled electric fields stimulation improve clinical outcomes after instrumented spinal fusion? A multicentered randomized, prospective, double-blind, placebo-controlled trial. Int J Spine Surg. 2020;14(6):936–943. doi: 10.14444/7142
  38. Andrade R, Duarte H, Pereira R, et al. Pulsed electromagnetic field therapy effectiveness in low back pain: a systematic review of randomized controlled trials. Porto Biomed J. 2016;1(5):156–163. doi: 10.1016/j.pbj.2016.09.001
  39. Griffin XL, Costa ML, Parsons N, et al.; Joint and Muscle Trauma Group, Electromagnetic field stimulation for treating delayed union or non-union of long bone fractures in adults. Cochrane Database Syst Rev. 2011;(4):CD008471. doi: 10.1002/14651858.CD008471.pub2
  40. Elshiwi M, Hamada HA, Mosaad D, et al. Effect of pulsed electromagnetic field on nonspecific low back pain patients: a randomized controlled trial. Braz J Phys Ther. 2019;23(3):244–249. doi: 10.1016/j.bjpt.2018.08.004
  41. Hattapoğlu E, Batmaz İ, Dilek B, et al. Efficiency of pulsed electromagnetic fields on pain, disability, anxiety, depression, and quality of life in patients with cervical disc herniation: a randomized controlled study. Turk J Med Sci. 2019;49(4):1095–1101. doi: 10.3906/sag-1901-65
  42. Catalano A, Loddo S, Bellone F, et al. Pulsed electromagnetic fields modulate bone metabolism via RANKL/OPG and Wnt/β-catenin pathways in women with postmenopausal osteoporosis: a pilot study. Bone. 2018;(116):42–46. doi: 10.1016/j.bone.2018.07.010
  43. Parhampour B, Torkaman G, Hoorfar H, et al. Effects of short-term resistance training and pulsed electromagnetic fields on bone metabolism and joint function in severe haemophilia A patients with osteoporosis: a randomized controlled trial. Clin Rehabil. 2014;28(5):440–450. doi: 10.1177/0269215513505299
  44. Zhou J, Liao Y, Xie H, et al. Effects of combined treatment with ibandronate and pulsed electromagnetic field on ovariectomy-induced osteoporosis in rats. Bioelectromagnetics. 2017;38(1):31–40. doi: 10.1002/bem.22012
  45. Jiang Y, Gou H, Wang S, et al. Effect of pulsed electromagnetic field on bone formation and lipid metabolism of glucocorticoid-induced osteoporosis rats through canonical Wnt signaling pathway. Evid Based Complement Alternat Med. 2016;2016:4927035. doi: 10.1155/2016/4927035
  46. Elsisi HF, Mousa GS, ELdesoky MT. Electromagnetic field versus circuit weight training on bone mineral density in elderly women. Clin Interv Aging. 2015;(10):539–547. doi: 10.2147/CIA.S78485
  47. Omar S, Awadalla MA, El-Latif MA. Evaluation of pulsed electromagnetic field therapy in the management of patients with discogenic lumbar radiculopathy. Int J Rheum Dis. 2012;15(5):e101–e108. doi: 10.1111/j.1756-185X.2012.01745.x
  48. Wang T, Yang L, Jiang J, et al. Pulsed electromagnetic fields: promising treatment for osteoporosis. Osteoporos Int. 2019;30(2): 267–276. doi: 10.1007/s00198-018-04822-6
  49. Hu H, Yang W, Zeng Q, et al. Promising application of pulsed electromagnetic fields in musculoskeletal disorders. Biomed Pharmacother. 2020;(131):110767. doi: 10.1016/j.biopha.2020.110767

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2022 Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86508 от 11.12.2023. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80650 от 15.03.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies