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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-title><trans-title-group xml:lang="ru"><trans-title>Физиотерапия, бальнеология и реабилитация</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1681-3456</issn><issn publication-format="electronic">2413-2969</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">677553</article-id><article-id pub-id-type="doi">10.17816/rjpbr677553</article-id><article-id pub-id-type="edn">JGVPQD</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Review</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Hemodynamic effects of electronic and conventional cigarette smoking: a meta-analysis</article-title><trans-title-group xml:lang="ru"><trans-title>Гемодинамические эффекты курения электронных сигарет и обычного табакокурения: метаанализ</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>电子烟与传统烟草吸烟的血流动力学效应： Meta分析</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-2706-7668</contrib-id><name-alternatives><name xml:lang="en"><surname>Pastarnakov</surname><given-names>Igor Yu.</given-names></name><name xml:lang="ru"><surname>Пастарнаков</surname><given-names>Игорь Юрьевич</given-names></name><name xml:lang="zh"><surname>Pastarnakov</surname><given-names>Igor Yu.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>igorpastarnakov19@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9715-5532</contrib-id><contrib-id contrib-id-type="spin">6038-5182</contrib-id><name-alternatives><name xml:lang="en"><surname>Kozyrev</surname><given-names>Oleg A.</given-names></name><name xml:lang="ru"><surname>Козырев</surname><given-names>Олег Анатольевич</given-names></name><name xml:lang="zh"><surname>Kozyrev</surname><given-names>Oleg A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><email>oak02@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Smolensk State Medical University</institution></aff><aff><institution xml:lang="ru">Смоленский государственный медицинский университет</institution></aff><aff><institution xml:lang="zh">Smolensk State Medical University</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-05-05" publication-format="electronic"><day>05</day><month>05</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2025</year></pub-date><volume>24</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>173</fpage><lpage>181</lpage><history><date date-type="received" iso-8601-date="2025-03-22"><day>22</day><month>03</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-04-04"><day>04</day><month>04</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://eco-vector.com/for_authors.php#07</ali:license_ref></license></permissions><self-uri xlink:href="https://rjpbr.com/1681-3456/article/view/677553">https://rjpbr.com/1681-3456/article/view/677553</self-uri><abstract xml:lang="en"><p>Currently electronic cigarettes are widely used as an alternative to conventional tobacco smoking, particularly among young people and individuals attempting to quit smoking. However, their impact on the cardiovascular system remains insufficiently understood and continues to generate debate within the scientific community. This meta-analysis aimed to assess the acute effects of nicotine-containing and nicotine-free electronic cigarettes on key hemodynamic parameters, including systolic blood pressure, diastolic blood pressure, and heart rate, in comparison with conventional cigarettes. The analysis included 22 studies published over the past 10 years (2014–2024), encompassing a total of 590 participants. Results of meta-analysis revealed that nicotine-containing electronic cigarettes produce statistically significant increases in systolic and diastolic blood pressure as well as heart rate. Conventional cigarettes demonstrated a similar effect on these indicators, although the magnitude of change was greater for nicotine-containing electronic cigarettes, likely due to the additional toxic components present in tobacco smoke. Notably, nicotine-free electronic cigarettes showed no statistically significant impact on the analyzed hemodynamic indicators. These results highlight the importance of considering the potential cardiovascular risks associated with electronic cigarette use, especially those containing nicotine. Further research is required to evaluate the long-term effects of electronic cigarettes use on cardiovascular system.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время электронные сигареты широко используются в качестве альтернативы обычному табакокурению, особенно среди молодежи и людей, стремящихся бросить курить. Однако их влияние на сердечно-сосудистую систему остаётся не до конца изученным и является предметом активных дискуссий в научном сообществе. Данный метаанализ проведён с целью оценить острое влияние электронных сигарет с никотином и без никотина на ключевые гемодинамические показатели, такие как систолическое артериальное давление, диастолическое артериальное давление и частота сердечных сокращений, в сравнении с воздействием обычных сигарет. В метаанализ включены 22 исследования, опубликованные за последние 10 лет (2014–2024 гг.), с общим числом участников 590 человек. Результаты метаанализа показали, что использование электронных сигарет с никотином вызывает статистически значимое повышение систолического и диастолического артериального давления, а также частоты сердечных сокращений. Обычные сигареты оказывают аналогичный эффект на эти показатели, однако величина изменений превышает таковую для электронных сигарет с никотином, что, вероятно, обусловлено воздействием дополнительных токсичных компонентов табачного дыма. Важно отметить, что электронные сигареты без никотина не продемонстрировали статистически значимого влияния на анализируемые гемодинамические показатели. Наши результаты подчёркивают важность учёта потенциальных сердечно-сосудистых рисков, связанных с использованием электронных сигарет, особенно содержащих никотин. Дальнейшие исследования необходимы для оценки долгосрочных эффектов использования электронных сигарет на сердечно-сосудистую систему.</p></trans-abstract><trans-abstract xml:lang="zh"><p>当前，电子烟作为传统烟草吸烟的替代选择被广泛使用，特别是在年轻人和有意戒烟的人群中。然而，其对心血管系统的影响尚未完全明确，仍是学术界争论的焦点之一。本Meta分析旨在评估含尼古丁和不含尼古丁的电子烟对关键血流动力学指标（包括收缩压、舒张压和心率）的急性影响，并与传统香烟的作用进行比较。Meta分析共纳入2014年至2024年间发表的22项研究，总参与人数为590人。结果显示，含尼古丁的电子烟会显著升高收缩压、舒张压和心率。传统香烟对上述指标亦具有类似作用，但升高幅度更大，这可能与烟草烟雾中其他有毒成分的影响有关。值得注意的是，不含尼古丁的电子烟对上述血流动力学参数未显示出统计学显著的影响。本研究结果强调，在评估电子烟，特别是含尼古丁产品的使用时，应充分考虑其潜在的心血管风险。未来仍需进一步研究以明确电子烟对心血管系统的长期影响。</p></trans-abstract><kwd-group xml:lang="en"><kwd>electronic cigarettes</kwd><kwd>cardiovascular system</kwd><kwd>blood pressure</kwd><kwd>heart rate</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>электронные сигареты</kwd><kwd>сердечно-сосудистая система</kwd><kwd>артериальное давление</kwd><kwd>частота сердечных сокращений</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>电子烟</kwd><kwd>心血管系统</kwd><kwd>血压</kwd><kwd>心率</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Dimitriadis K, Narkiewicz K, Leontsinis I, et al. 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