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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-title><trans-title-group xml:lang="ru"><trans-title>Физиотерапия, бальнеология и реабилитация</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1681-3456</issn><issn publication-format="electronic">2413-2969</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">115065</article-id><article-id pub-id-type="doi">10.17816/rjpbr115065</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Review</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Correction of age-related changes of the face skin using radiofrequency micro needling. Brief literature review</article-title><trans-title-group xml:lang="ru"><trans-title>Коррекция возрастных изменений кожи лица с помощью радиочастотного микроигольчатого метода. Краткий обзор литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7840-4000</contrib-id><contrib-id contrib-id-type="spin">6271-4475</contrib-id><name-alternatives><name xml:lang="en"><surname>Agapova</surname><given-names>Marina A.</given-names></name><name xml:lang="ru"><surname>Агапова</surname><given-names>Марина Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>marinaagapova505@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2148-5740</contrib-id><contrib-id contrib-id-type="spin">8764-2335</contrib-id><name-alternatives><name xml:lang="en"><surname>Sharova</surname><given-names>Alisa А.</given-names></name><name xml:lang="ru"><surname>Шарова</surname><given-names>Алиса Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, D. Sci. (Med.), Assistant Professor</p></bio><bio xml:lang="ru"><p>д.м.н., доцент</p></bio><email>aleca@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Swiss Center for Rejuvenation Versua Cliniс</institution></aff><aff><institution xml:lang="ru">Швейцарский центр омоложения Versua Clinic</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Center for Aesthetic Medicine "Chistye Prudy"</institution></aff><aff><institution xml:lang="ru">Центр эстетической медицины «Чистые пруды»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-12-06" publication-format="electronic"><day>06</day><month>12</month><year>2022</year></pub-date><volume>21</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>289</fpage><lpage>299</lpage><history><date date-type="received" iso-8601-date="2022-12-05"><day>05</day><month>12</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-12-05"><day>05</day><month>12</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Эко-Вектор"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder></permissions><self-uri xlink:href="https://rjpbr.com/1681-3456/article/view/115065">https://rjpbr.com/1681-3456/article/view/115065</self-uri><abstract xml:lang="en"><p>The problem of choosing a method for skin rejuvenation remains relevant despite a wide selection of conservative and surgical methods for eliminating age-related changes. In recent years, treatment methods for voluminous and traumatic ones have been striving for minimally invasive, quickly feasible with an optimal result that should meet both the needs of patients and doctors. For this reason, injection and hardware methods of rejuvenation began to come to the fore, especially when correcting changes on the face. Cosmetic devices based on radiofrequency can compete in efficiency with laser technology, having their own specific advantages.</p> <p>The aim of the work was to evaluate the available literature sources related to the use of radiofrequency in dermatology and dermatocosmetology, especially for leveling age-related changes in the skin of the face.</p> <p>The available literature sources from Russian and foreign databases (Elibrary, PubMed, Google Academia) were analyzed on the use of radiofrequency and radiofrequency micro needling in dermatocosmetology for facial skin rejuvenation.</p> <p>The analysis showed the widespread use of radio frequency in dermatocosmetology, its high efficiency and safety, however, there are very few full-fledged studies devoted to radio frequency microneedling.</p> <p>In our opinion, radiofrequency microneedling is a significant step forward compared to traditional radiofrequency devices, especially for facial skin rejuvenation by increasing the safety and effectiveness of the procedure. The use of radiofrequency microneedling can be effective for correcting age-related skin changes, especially in the face area, both as monotherapy and in combination with other methods of rejuvenation.</p></abstract><trans-abstract xml:lang="ru"><p>Проблема выбора метода омоложения кожи остаётся актуальной, несмотря на широкий выбор консервативных и хирургических методов устранения возрастных изменений. В последние годы методы лечения от объёмных и травматических стремятся к малоинвазивным, быстро выполнимым при достижении оптимального результата, который должен отвечать как запросам пациентов, так и врачей. По этой причине на первый план стали выходить инъекционные и аппаратные методы омоложения, особенно при коррекции изменений на лице. Косметологические аппараты на основе радиочастоты могут поспорить в эффективности с лазерными технологиями, обладая своими определёнными преимуществами.</p> <p>Целью работы являлась оценка доступных источников литературы, связанных с применением радиочастоты в дерматологии и дерматокосметологии, особенно для нивелирования возрастных изменений кожи лица.</p> <p>Проанализированы доступные источники литературы из российских и зарубежных баз данных (Elibrary, PubMed, Google Academia) по теме применения радиочастоты и радиочастотного микроигольчатого воздействия в дерматокосметологии для омоложения кожи лица.</p> <p>Анализ показал широкое применения радиочастоты в дерматокосметологии, её высокую эффективность и безопасность, однако полноценных исследований, посвящённых радиочастотному микроигольчатому методу, крайне мало.</p> <p>Радиочастотный микроигольчатый метод, на наш взгляд, является значительным шагом вперёд по сравнению с традиционными радиочастотными устройствами, особенно для подтяжки кожи лица, за счёт увеличения безопасности и эффективности процедуры. Применение радиочастотного микроигольчатого метода может быть эффективным для коррекции возрастных изменений кожи, в частности в области лица, как в виде монотерапии, так и в сочетании с другими методами омоложения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>radiofrequency micro needling</kwd><kwd>heating</kwd><kwd>rejuvenation</kwd><kwd>skin</kwd><kwd>face</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>радиочастотный микроигольчатый метод</kwd><kwd>нагревание</kwd><kwd>омоложение</kwd><kwd>кожа</kwd><kwd>лицо</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Belenky I, Margulis A, Elman M, et al. Exploring channeling optimized radiofrequency energy: A review of radiofrequency history and applications in esthetic fields. Adv Ther. 2012;29(3):249–266. doi: 10.1007/s12325-012-0004-1</mixed-citation><mixed-citation xml:lang="ru">Belenky I., Margulis A., Elman M., et al. Exploring channeling optimized radiofrequency energy: A review of radiofrequency history and applications in esthetic fields // Adv Ther. 2012. Vol. 29, N 3. Р. 249–266. doi: 10.1007/s12325-012-0004-1</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Schepps JL, Foster KR. The UHF and microwave dielectric properties of normal and tumour tissues: variation in dielectric properties with tissue water content. Phys Med Biol. 1980;25(6):1149–1159. doi: 10.1088/0031-9155/25/6/012</mixed-citation><mixed-citation xml:lang="ru">Schepps J.L., Foster K.R. The UHF and microwave dielectric properties of normal and tumour tissues: Variation in dielectric properties with tissue water content // Phys Med Biol. 1980. Vol. 25, N 6. Р. 1149–1159. doi: 10.1088/0031-9155/25/6/012</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Weiner SF. Radiofrequency microneedling: overview of technology, advantages, differences in devices, studies, and indications. Facial Plastic Sur Clin. 2019;27(3):291–303. doi: 10.1016/j.fsc.2019.03.002</mixed-citation><mixed-citation xml:lang="ru">Weiner S.F. Radiofrequency microneedling: Overview of technology, advantages, differences in devices, studies, and indications // Facial Plastic Sur Clin. 2019. Vol. 27, N 3. Р. 291–303. doi: 10.1016/j.fsc.2019.03.002</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Sadick NS, Makino Y. Selective electro-thermolysis in aesthetic medicine: A review. Lasers Surg Med. 2004;34(2):91–97. doi: 10.1002/lsm.20013</mixed-citation><mixed-citation xml:lang="ru">Sadick N.S., Makino Y. Selective electro-thermolysis in aesthetic medicine: A review // Lasers Surg Med. 2004. Vol. 34, N 2. Р. 91–97. doi: 10.1002/lsm.20013</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Gold MH. The increasing use of nonablative radiofrequency in the rejuvenation of the skin. Expert Rev Dermatol. 2011;6(2): 139–143. doi: 10.1586/edm.11.11</mixed-citation><mixed-citation xml:lang="ru">Gold M.H. The increasing use of nonablative radiofrequency in the rejuvenation of the skin // Expert Rev Dermatol. 2011. Vol. 6, N 2. Р. 139–143. doi: 10.1586/edm.11.11</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Beasley KL, Weiss RA. Radiofrequency in cosmetic dermatology. Dermatol Clin. 2014;32(1):79–90. doi: 10.1016/j.det.2013.09.010</mixed-citation><mixed-citation xml:lang="ru">Beasley K.L., Weiss R.A. Radiofrequency in cosmetic dermatology // Dermatol Clin. 2014. Vol. 32, N 1. Р. 79–90. doi: 10.1016/j.det.2013.09.010</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Alster TS, Lupton JR. Nonablative cutaneous remod-eling using radiofrequency devices. Clin Dermatol. 2007;25(5):487–491. doi: 10.1016/j.clindermatol.2007.05.005</mixed-citation><mixed-citation xml:lang="ru">Alster T.S., Lupton J.R. Nonablative cutaneous remod-eling using radiofrequency devices // Clin Dermatol. 2007. Vol. 25, N 5. Р. 487–491. doi: 10.1016/j.clindermatol.2007.05.005</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Clementoni MT, Munavalli GS. Fractional high inten-sity focused radiofrequency in the treatment of mild to moderate laxity of the lower face and neck: A pilot study. Lasers Surg Med. 2016;48(5):461–470. doi: 10.1002/lsm.22499</mixed-citation><mixed-citation xml:lang="ru">Clementoni M.T., Munavalli G.S. Fractional high inten-sity focused radiofrequency in the treatment of mild to moderate laxity of the lower face and neck: A pilot study // Lasers Surg Med. 2016. Vol. 48, N 5. Р. 461–470. doi: 10.1002/lsm.22499</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Hayashi K, Thabit G, Massa KL, et al. The effect of thermal heating on the length and histologic properties of the glenohumeral joint capsule. Am J Sports Med. 1997;25(1):107–12. doi: 10.1177/036354659702500121</mixed-citation><mixed-citation xml:lang="ru">Hayashi K., Thabit G., Massa K.L., et al. The effect of thermal heating on the length and histologic properties of the glenohumeral joint capsule // Am J Sports Med. 1997. Vol. 25, N 1. Р. 107–112. doi: 10.1177/036354659702500121</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Yeo UCh, Lee DR, Lim SD. Histologic evaluation of deep dermal heating by fractional radiofrequency according to energy. In: ASLMS 30th Annual Conference 2010 Phoenix Convention Center, Phoenix, Arizona. Available from: https://perigee.com/wp-content/uploads/INTRAcel-Jeisys-Article.pdf. Accessed: 15.07.2022.</mixed-citation><mixed-citation xml:lang="ru">Yeo U.Ch., Lee D.R., Lim S.D. Histologic evaluation of deep dermal heating by fractional radiofrequency according to energy // ASLMS 30th Annual Conference 2010 Phoenix Convention Center, Phoenix, Arizona. Режим доступа: https://perigee.com/wp-content/uploads/INTRAcel-Jeisys-Article.pdf. Дата обращения: 15.07.2022.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Abraham MT, Ross VE. Current concepts in nonablative radiofrequency rejuvenation of the lower face and neck. Facial Plast Surg. 2005;21(1):65–73. doi: 10.1055/s-2005-871765</mixed-citation><mixed-citation xml:lang="ru">Abraham M.T., Ross V.E. Current concepts in nonablative radiofrequency rejuvenation of the lower face and neck // Facial Plast Surg. 2005. Vol. 21, N 1. Р. 65–73. doi: 10.1055/s-2005-871765</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Bernstein LJ, Kauvar AN, Grossman MC, et al. The short- and long-term side effects of carbon dioxide laser resurfacing. Dermatol Surg. 1997;23(7):519–525. doi: 10.1111/j.1524-4725.1997.tb00677.x</mixed-citation><mixed-citation xml:lang="ru">Bernstein L.J., Kauvar A.N., Grossman M.C., et al. The short- and long-term side effects of carbon dioxide laser resurfacing // Dermatol Surg. 1997. Vol. 23, N 7. Р. 519–525. doi: 10.1111/j.1524-4725.1997.tb00677.x</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Hantash BM, Renton B, Berkowitz RL, et al. Pilot clinical study of a novel minimally invasive bipolar microneedle radiofrequency device. Lasers Surg Med. 2009;41(2):87–95. doi: 10.1002/lsm.20687</mixed-citation><mixed-citation xml:lang="ru">Hantash B.M., Renton B., Berkowitz R.L., et al. Pilot clinical study of a novel minimally invasive bipolar microneedle radiofrequency device // Lasers Surg Med. 2009. Vol. 41, N 2. Р. 87–95. doi: 10.1002/lsm.20687</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Hantash BM, Ubeid AA, Chang H, et al. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis. Lasers Surg Med. 2009;41(1):1–9. doi: 10.1002/lsm.20731</mixed-citation><mixed-citation xml:lang="ru">Hantash B.M., Ubeid A.A., Chang H., et al. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis // Lasers Surg Med. 2009. Vol. 41, N 1. Р. 1–9. doi: 10.1002/lsm.20731</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Zheng Z, Goo B, Kim DY, et al. Histometric analysis of skin-radiofrequency interaction using a fractionated microneedle delivery system. Dermatol Surg. 2014;40(2):134–141. doi: 10.1111/dsu.12411</mixed-citation><mixed-citation xml:lang="ru">Zheng Z., Goo B., Kim D.Y., et al. Histometric analysis of skin-radiofrequency interaction using a fractionated microneedle delivery system // Dermatol Surg. 2014. Vol. 40, N 2. Р. 134–141. doi: 10.1111/dsu.12411</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Thomsen S. Pathologic analysis of photothermal and photomechanical effects of laser-tissue interactions. Photochem Photobiol. 1991;53(6):825–835. doi: 10.1111/j.1751-1097.1991.tb09897.x</mixed-citation><mixed-citation xml:lang="ru">Thomsen S. Pathologic analysis of photothermal and photomechanical effects of laser-tissue interactions // Photochem Photobiol. 1991. Vol. 53, N 6. Р. 825–835. doi: 10.1111/j.1751-1097.1991.tb09897.x</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">Sadick N. Tissue tightening technologies: fact or fiction. Aesthet Surg J. 2008;28(2):180–188. doi: 10.1016/j.asj.2007.12.009</mixed-citation><mixed-citation xml:lang="ru">Sadick N. Tissue tightening technologies: Fact or fiction // Aesthet Surg J. 2008. Vol. 28, N 2. Р. 180–188. doi: 10.1016/j.asj.2007.12.009</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">Zelickson BD, Kist D, Bernstein E, et al. Histological and ultrastructural evaluation of the effects of a radiofrequency-based nonablative dermal remodeling device. Arch Dermatol. 2004;140(2):204–209. doi: 10.1001/archderm.140.2.204</mixed-citation><mixed-citation xml:lang="ru">Zelickson B.D., Kist D., Bernstein E., et al. Histological and ultrastructural evaluation of the effects of a radiofrequency-based nonablative dermal remodeling device // Arch Dermatol. 2004. Vol. 140, N 2. Р. 204–209. doi: 10.1001/archderm.140.2.204</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">Kuo T, Speyer MT, Ries WR, et al. Collagen thermal damage and collagen synthesis after cutaneous laser resurfacing. Lasers Surg Med. 1998;23(2):66–71. doi: 10.1002/(sici)1096-9101(1998)23:2&lt;66::aid-lsm3&gt;3.0.co;2-t</mixed-citation><mixed-citation xml:lang="ru">Kuo T., Speyer M.T., Ries W.R., et al. Collagen thermal damage and collagen synthesis after cutaneous laser resurfacing // Lasers Surg Med. 1998. Vol. 23, N 2. Р. 66–71. doi: 10.1002/(sici)1096-9101(1998)23:2&lt;66::aid-lsm3&gt;3.0.co;2-t</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">Goldberg DJ. Nonablative dermal remodeling: Does it really work? Arch Dermatol. 2002;138(10):1366–1368. doi: 10.1001/archderm.138.10.1366</mixed-citation><mixed-citation xml:lang="ru">Goldberg D.J. Nonablative dermal remodeling: Does it really work? // Arch Dermatol. 2002. Vol. 138, N 10. Р. 1366–1368. doi: 10.1001/archderm.138.10.1366</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">Hruza G, Taub AF, Collier SL, et al. Skin rejuvenation and wrinkle reduction using a fractional radiofrequency system. J Drugs Dermatol. 2009;8(3):259–265.</mixed-citation><mixed-citation xml:lang="ru">Hruza G., Taub A.F., Collier S.L., et al. Skin rejuvenation and wrinkle reduction using a fractional radiofrequency system // J Drugs Dermatol. 2009. Vol. 8, N 3. Р. 259–265.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">Phothong W, Wanitphakdeedecha R, Sathaworawong A, Manuskiatti W. High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars: A split-face double-blinded randomized control trial pilot study. Lasers Med Sci. 2016;31(2):229–234. doi: 10.1007/s10103-015-1850-2</mixed-citation><mixed-citation xml:lang="ru">Phothong W., Wanitphakdeedecha R., Sathaworawong A., Manuskiatti W. High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars: A split-face double-blinded randomized control trial pilot study // Lasers Med Sci. 2016. Vol. 31, N 2. Р. 229–234. doi: 10.1007/s10103-015-1850-2</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">Martin J. Review of fractional microneedling radiofrequency for skin rejuvenation. Prime. 2018. Available from: https://www.prime-journal.com/review-of-fractionated-microneedle-radiofrequency-for-skin-rejuvenation/. Accessed: 15.07.2022.</mixed-citation><mixed-citation xml:lang="ru">Martin J. Review of fractional microneedling radiofrequency for skin rejuvenation // Prime. 2018. Режим доступа: https://www.prime-journal.com/review-of-fractionated-microneedle-radiofrequency-for-skin-rejuvenation/. Дата обращения: 15.07.2022.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">Park JY, Lee EG, Yoon MS, et al. The efficacy and safety of combined microneedle fractional radiofrequency and sublative fractional radiofrequency for acne scars in Asian skin. J Cosmet Dermatol. 2016;15(2):102–107. doi: 10.1111/jocd.12195</mixed-citation><mixed-citation xml:lang="ru">Park J.Y., Lee E.G., Yoon M.S., et al. The efficacy and safety of combined microneedle fractional radiofrequency and sublative fractional radiofrequency for acne scars in Asian skin // J Cosmet Dermatol. 2016. Vol. 15, N 2. Р. 102–107. doi: 10.1111/jocd.12195</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">Cohen JL, Weiner SF, Pozner JN, et al. Multi-center pilot study to evaluate the safety profile of high energy fractionated radiofrequency with insulated microneedles to multiple levels of the dermis. J Drugs Dermatol. 2016;15(11):1308–1312.</mixed-citation><mixed-citation xml:lang="ru">Cohen J.L., Weiner S.F., Pozner J.N., et al. Multi-Center Pilot Study to evaluate the safety profile of high energy fractionated radiofrequency with insulated microneedles to multiple levels of the dermis // J Drugs Dermatol. 2016. Vol. 15, N 11. Р. 1308–1312.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">Chandrashekar BS, Sriram R, Mysore R, et al. Evaluation of microneedling fractional radiofrequency device for treatment of acne scars. J Cutan Aesthet Surg. 2014;7(2):93–97. doi: 10.4103/0974-2077.138328</mixed-citation><mixed-citation xml:lang="ru">Chandrashekar B.S., Sriram R., Mysore R., et al. Evaluation of microneedling fractional radiofrequency device for treatment of acne scars // J Cutan Aesthet Surg. 2014. Vol. 7, N 2. Р. 93–97. doi: 10.4103/0974-2077.138328</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">Clementoni MT, Munavalli GS. Fractional high intensity focused radiofrequency in the treatment of mild to moderate laxity of the lower face and neck: a pilot study. Lasers Surg Med. 2016;48(5):461–470. doi: 10.1002/lsm.22499</mixed-citation><mixed-citation xml:lang="ru">Clementoni M.T., Munavalli G.S. Fractional high intensity focused radiofrequency in the treatment of mild to moderate laxity of the lower face and neck: A pilot study // Lasers Surg Med. 2016. Vol. 48, N 5. Р. 461–470. doi: 10.1002/lsm.22499</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">Ibrahimi OA, Weiss RA, Weiss MA, et al. Treatment of acne scars with high intensity focused radio frequency. J Drugs Dermatol. 2015;14(9):1065–1068.</mixed-citation><mixed-citation xml:lang="ru">Ibrahimi O.A., Weiss R.A., Weiss M.A., et al. Treatment of acne scars with high intensity focused radio frequency // J Drugs Dermatol. 2015. Vol. 14, N 9. Р. 1065–1068.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">Alexiades-Armenakas M, Rosenberg D, Renton B, et al. Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity. Arch Dermatol. 2010;146(4):396–405. doi: 10.1001/archdermatol.2010.24</mixed-citation><mixed-citation xml:lang="ru">Alexiades-Armenakas M., Rosenberg D., Renton B., et al. Blinded, randomized, quantitative grading comparison of minimally invasive, fractional radiofrequency and surgical face-lift to treat skin laxity // Arch Dermatol. 2010. Vol. 146, N 4. Р. 396–405. doi: 10.1001/archdermatol.2010.24</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">Alexiades-Armenakas M, Newman J, Willey A, et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment. Dermatol Surg. 2013;39(2):263–273. doi: 10.1111/dsu.12065</mixed-citation><mixed-citation xml:lang="ru">Alexiades-Armenakas M., Newman J., Willey A., et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment // Dermatol Surg. 2013. Vol. 39, N 2. Р. 263–273. doi: 10.1111/dsu.12065</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">Calderhead RG, Goo BL, Lauro F, et al. The clinical efficacy and safety of microneedling fractional radiofrequency in the treatment of facial wrinkles: A multicenter study with the INFINI system in 499 patients. 2013. Available from: https://www.semanticscholar.org/paper/The-Clinical-Efficacy-and-Safety-of-Microneedling-%3A-Calderhead-Goo/729b55ce2cdc8e4b43da9f86c5d865662c9351c7. Accessed: 15.07.2022.</mixed-citation><mixed-citation xml:lang="ru">Calderhead R.G., Goo B.L., Lauro F., et al. The clinical efficacy and safety of microneedling fractional radiofrequency in the treatment of facial wrinkles: A multicenter study with the INFINI system in 499 patients. 2013. Режим доступа: https://www.semanticscholar.org/paper/The-Clinical-Efficacy-and-Safety-of-Microneedling-%3A-Calderhead-Goo/729b55ce2cdc8e4b43da9f86c5d865662c9351c7. Дата обращения: 15.07.2022.</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">Kim JK, Roh MR, Park GH, et al. Fractionated microneedle radiofrequency for the treatment of periorbital wrinkles. J Dermatol. 2013;40(3):172–176. doi: 10.1111/1346-8138</mixed-citation><mixed-citation xml:lang="ru">Kim J.K., Roh M.R., Park G.H., et al. Fractionated microneedle radiofrequency for the treatment of periorbital wrinkles // J Dermatol 2013. Vol. 40, N 3. Р. 172–176. doi: 10.1111/1346-8138</mixed-citation></citation-alternatives></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">Alenichev AY, Kruglova LS, Fedorov SM, et al. Combined use of microneedle RF therapy and injections of platelet-rich plasma activated by autologous thrombin in aesthetic medicine. Russian journal of the physial therapy, balneotherapy and rehabilitation. 2017;16(5):320–324. (In Russ). doi: 10.18821/1681-3456-2017-16-5-320-324</mixed-citation><mixed-citation xml:lang="ru">Аленичев А.Ю., Круглова Л.С., Федоров С.М., и др. Комбинированное применение микроигольной RF-терапии и инъекций богатой тромбоцитами плазмы, активированной аутологичным тромбином в эстетической медицине // Физиотерапия, бальнеология и реабилитация. 2017. Т. 16, № 5. С. 320–324. doi: 10.18821/1681-3456-2017-16-5-320-324</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><citation-alternatives><mixed-citation xml:lang="en">Kwon SH, Choi JY, Ahn GY, et al. The efficacy and safety of microneedle monopolar radiofrequency for the treatment of periorbital wrinkles. J Dermatol Treatment. 2019;32(4):460–464. doi: 10.1080/09546634.2019.1662880</mixed-citation><mixed-citation xml:lang="ru">Kwon S.H., Choi J.Y., Ahn G.Y., et al. The efficacy and safety of microneedle monopolar radiofrequency for the treatment of periorbital wrinkles // J Dermatol Treatment. 2019. Vol. 32, N 4. Р. 460–464. doi: 10.1080/09546634.2019.1662880</mixed-citation></citation-alternatives></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">Naeini F, Abtahi-Naeini B, Pourazizi M, et al. Fractionated microneedle radiofrequency for treatment of primary axillary hyperhidrosis: A sham control study. Australas J Dermatol. 2015;56(4):279–284. doi: 10.1111/ajd.12260</mixed-citation><mixed-citation xml:lang="ru">Naeini F., Abtahi-Naeini B., Pourazizi M., et al. Fractionated microneedle radiofrequency for treatment of primary axillary hyperhidrosis: A sham control study // Australas J Dermatol. 2015. Vol. 56, N 4. Р. 279–284. doi: 10.1111/ajd.12260</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">Alexiades M, Munavalli G, Goldberg D, et al. Prospective multicenter clinical trial of a temperaturecontrolled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite. Dermatol Surg. 2018;44(10):1262–1271. doi: 10.1097/DSS.0000000000001593</mixed-citation><mixed-citation xml:lang="ru">Alexiades M., Munavalli G., Goldberg D., et al. Prospective multicenter clinical trial of a temperaturecontrolled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite // Dermatol Surg. 2018. Vol. 44, N 10. Р. 1262–1271. doi: 10.1097/DSS.0000000000001593</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><citation-alternatives><mixed-citation xml:lang="en">Yu AJ, Luo YJ, Xu XG, et al. A pilot split-scalp study of combined fractional radiofrequency microneedling and 5% topical minoxidil in treating male pattern hair loss. Clin Exp Dermatol. 2018; 43(7):775–781. doi: 10.1111/ced.13551</mixed-citation><mixed-citation xml:lang="ru">Yu A.J., Luo Y.J., Xu X.G., et al. A pilot split-scalp study of combined fractional radiofrequency microneedling and 5% topical minoxidil in treating male pattern hair loss // Clin. Exp. Dermatol. 2018. Vol. 43, N 7. P. 775–781. doi: 10.1111/ced.13551</mixed-citation></citation-alternatives></ref><ref id="B38"><label>38.</label><citation-alternatives><mixed-citation xml:lang="en">Calderhead G. Combining microneedle fractional radiofrequency and LED photoactivation. Prime. 2014;2(6):15–23.</mixed-citation><mixed-citation xml:lang="ru">Calderhead G. Combining microneedle fractional radiofrequency and LED photoactivation // Prime. 2014. Vol. 2, N 6. Р. 15–23.</mixed-citation></citation-alternatives></ref><ref id="B39"><label>39.</label><citation-alternatives><mixed-citation xml:lang="en">Kruglova LS, Kotenko KV, Korchazhkina NB, Turbovskaya SN. Physiotherapy in dermatology. Moscow: GEOTAR-Media; 2016. 304 p. (In Russ).</mixed-citation><mixed-citation xml:lang="ru">Круглова Л.С., Котенко К.В., Корчажкина Н.Б., Турбовская С.Н. Физиотерапия в дерматологии. Москва: ГЭОТАР-Медиа, 2016. 304 с.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
