<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Physiotherapy, Balneology and Rehabilitation</journal-title><trans-title-group xml:lang="ru"><trans-title>Физиотерапия, бальнеология и реабилитация</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1681-3456</issn><issn publication-format="electronic">2413-2969</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">106153</article-id><article-id pub-id-type="doi">10.17816/1681-3456-2021-20-209-220</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original studies</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Complex treatment of patients with hormone-dependent atrophic scars</article-title><trans-title-group xml:lang="ru"><trans-title>Комплексное лечение пациентов с гормонально-зависимыми атрофическими рубцами</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0850-3238</contrib-id><name-alternatives><name xml:lang="en"><surname>Talibova</surname><given-names>Aliya P.</given-names></name><name xml:lang="ru"><surname>Талыбова</surname><given-names>Алия Пашаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>tynrik@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3437-5233</contrib-id><contrib-id contrib-id-type="spin">1309-4668</contrib-id><name-alternatives><name xml:lang="en"><surname>Gryazeva</surname><given-names>Natalia V.</given-names></name><name xml:lang="ru"><surname>Грязева</surname><given-names>Наталья Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>tynrik@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6153-9673</contrib-id><name-alternatives><name xml:lang="en"><surname>Elfimov</surname><given-names>Mikhail A.</given-names></name><name xml:lang="ru"><surname>Елфимов</surname><given-names>Михаил Алексеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>д.м.н.</p></bio><email>tynrik@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Central State Medical Academy of Department of Presidential Affairs</institution></aff><aff><institution xml:lang="ru">Центральная государственная медицинская академия Управления делами Президента Российской Федерации</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institutes of Plastic Surgery and Cosmetology</institution></aff><aff><institution xml:lang="ru">Институт пластической хирургии и косметологии</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2021</year></pub-date><volume>20</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>209</fpage><lpage>220</lpage><history><date date-type="received" iso-8601-date="2022-04-10"><day>10</day><month>04</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-04-10"><day>10</day><month>04</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Эко-Вектор"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2024-05-15"/></permissions><self-uri xlink:href="https://rjpbr.com/1681-3456/article/view/106153">https://rjpbr.com/1681-3456/article/view/106153</self-uri><abstract xml:lang="en"><p><bold><italic>BACKGROUND</italic></bold><italic>: </italic>There are a large number of different methods of treating striae, starting with local therapy with various oils, ending with hardware techniques, but standardized treatment protocols have not yet been developed, which forces us to look for new promising combined treatment regimens</p> <p><bold><italic>AIMS</italic></bold><italic>:</italic> To study the effectiveness of therapeutic complexes in patients with atrophic hormone-dependent scars.</p> <p><bold><italic>MATERIAL AND METHODS</italic></bold><italic>:</italic> 145 patients with hormone-dependent scars with different AP phenotypes were followed up. In groups 1A and 1B, phototherapy was performed using broadband incoherent light-IPL therapy. In groups 2A and 2B, exposure was performed using bipolar fractional radiofrequency therapy. In groups 3A and 3B, the patient underwent a mesoroller microneedling procedure. PRP therapy was performed in groups 1B, 2B, and 3B. A visual analog scale (VAS) was used to evaluate the effectiveness.</p> <p><bold><italic>RESULTS</italic></bold><italic>: </italic>Comparing the data obtained, it should be noted that, regardless of the age of the scar (red, white), the developed complex methods of therapy showed greater effectiveness than monotherapy with pulsed broadband light, RF microneedles or microneedling.</p> <p><bold><italic>CONCLUSION</italic></bold><italic>:</italic> The combination of RF-therapy and PRP-therapy showed the greatest effectiveness against all clinical symptoms of AR, IPL-therapy with plasma with cells and plasma-with-cells microneedling showed a comparable high efficiency in different periods of AR existence.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование</bold>. Известно большое количество методов лечения стрий ― от местной терапии различными маслами до аппаратных методик, однако стандартизированного протокола лечения до сих пор не разработано, что заставляет искать новые перспективные комбинированные схемы лечения.</p> <p><bold>Цель исследования</bold> ― изучить эффективность терапевтических комплексов у пациентов с атрофическими гормонально-зависимыми рубцами.</p> <p><bold>Материал и методы</bold>. Под наблюдением находилось 145 пациентов с атрофическими гормонально-зависимыми рубцами разных фенотипов. В группах 1А и 1В проводилась фототерапия с использованием широкополосного некогерентного света (IPL-терапия); в группах 2А и 2В ― биполярная фракционная радиочастотная терапия; в группах 3А и 3В ― процедура микронидлинга мезороллером. В каждую подгруппу В дополнительно была введена PRP-терапия. Для оценки эффективности использовалась визуальная аналоговая шкала.</p> <p><bold>Результаты</bold>. Сравнивая полученные данные, следует отметить, что разработанные комплексные методы терапии показали бÓльшую эффективность независимо от давности рубца (красный, белый), чем монотерапия импульсным широкополосным светом, RF-микроиглами или микронидлинг.</p> <p><bold>Заключение</bold>. Комбинация RF- и PRP-терапии показала наибольшую эффективность в отношении всех клинических симптомов атрофических рубцов, IPL-терапия с плазмой с клетками и микронидлинг плазмы с клетками ― сопоставимую высокую эффективность при различных по давности существования атрофических рубцах.</p></trans-abstract><kwd-group xml:lang="en"><kwd>atrophic hormone-dependent scars</kwd><kwd>laser therapy</kwd><kwd>microneedle radiofrequency therapy</kwd><kwd>microneedling</kwd><kwd>autologous plasma with cells</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>атрофические гормонально-зависимые рубцы</kwd><kwd>лазерная терапия</kwd><kwd>микроигольчатая радиочастотная терапия</kwd><kwd>микронидлинг</kwd><kwd>аутологичная плазма с клетками</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Thomas RG, Liston WA. Clinical associations of striae gravidarum. J Obstet Gynaecol. 2004;24(3):270–271. doi: 10.1080/014436104101001660779</mixed-citation><mixed-citation xml:lang="ru">Thomas R.G., Liston W.A. Clinical associations of striae gravidarum // J Obstet Gynaecol. 2004. Vol. 24, N 3. P. 270–271. doi: 10.1080/014436104101001660779</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Yamaguchi K, Suganuma N, Ohashi K. Quality of life evaluation in Japanese pregnant women with striae gravidarum: a cross-sectional study. BMC Res Notes. 2012;5:450. doi: 10.1186/1756-0500-5-450</mixed-citation><mixed-citation xml:lang="ru">Yamaguchi K., Suganuma N., Ohashi K. Quality of life evaluation in Japanese pregnant women with striae gravidarum: a cross-sectional study // BMC Res Notes. 2012. Vol. 5. P. 450. doi: 10.1186/1756-0500-5-450</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Atwal GS, Manku LK, Griffiths CE, Polson DW. Striae gravidarum in primiparae. Br J Dermatol. 2006;155(5):965–969. doi: 10.1111/j.1365-2133.2006.07427.x</mixed-citation><mixed-citation xml:lang="ru">Atwal G.S., Manku L.K., Griffiths C.E., Polson D.W. Striae gravidarum in primiparae // Br J Dermatol. 2006. Vol. 155, N 5. P. 965–969. doi: 10.1111/j.1365-2133.2006.07427.x</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Watson RE. Stretching the point: an association between the occurrence of striae and pelvic relaxation? J Invest Dermatol. 2006;126(8):1688–1689. doi: 10.1038/sj.jid.5700316</mixed-citation><mixed-citation xml:lang="ru">Watson R.E. Stretching the point: an association between the occurrence of striae and pelvic relaxation? // J Invest Dermatol. 2006. Vol. 126, N 8. P. 1688–1689. doi: 10.1038/sj.jid.5700316</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Khatri KA, Mahoney DL, McCartney MJ. Laser scar revision: a review. J Cosmet Laser Ther. 2011;13(2):54–62. doi: 10.3109/14764172.2011.564625</mixed-citation><mixed-citation xml:lang="ru">Khatri K.A., Mahoney D.L., McCartney M.J. Laser scar revision: a review // J Cosmet Laser Ther. 2011. Vol. 13, N 2. P. 54–62. doi: 10.3109/14764172.2011.564625</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Brewin MP, Lister TS. Prevention or treatment of hypertrophic burn scarring: a review of when and how to treat with the pulsed dye laser. Burns. 2014;40(5):797–804. doi: 10.1016/j.burns.2013.12.017</mixed-citation><mixed-citation xml:lang="ru">Brewin M.P., Lister T.S. Prevention or treatment of hypertrophic burn scarring: a review of when and how to treat with the pulsed dye laser // Burns. 2014. Vol. 40, N 5. P. 797–804. doi: 10.1016/j.burns.2013.12.017</mixed-citation></citation-alternatives></ref></ref-list></back></article>
