Synthesis and transformations of O-propargyl analogues of fusidic acid

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Abstract

In continuation of the studies on synthetic modifications of fusidane triterpenoids, an O-propargyl fragment was introduced at the C3 atom of the fusidic acid methyl ester molecule and chemical transformations of the triple bond were carried out through reactions catalyzed by copper(I) salts to obtain an aminomethylene analogue, 1,2,3-triazole, and an aryl-substituted acetylene derivative.

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About the authors

E. V. Salimova

Ufa Federal Research Center, Russian Academy of Sciences

Author for correspondence.
Email: salimovaev@mail.ru
ORCID iD: 0000-0002-4328-5080

Institute of Petrochemistry and Catalysis

Russian Federation, prosp. Oktyabrya, 141, Ufa, 450075

D. A. Golovnina

Ufa Federal Research Center, Russian Academy of Sciences

Email: salimovaev@mail.ru

Institute of Petrochemistry and Catalysis

Russian Federation, prosp. Oktyabrya, 141, Ufa, 450075

L. V. Parfenova

Ufa Federal Research Center, Russian Academy of Sciences

Email: salimovaev@mail.ru
ORCID iD: 0000-0003-2816-2178

Institute of Petrochemistry and Catalysis

Russian Federation, prosp. Oktyabrya, 141, Ufa, 450075

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